粤东地区儿童过敏性紫癜526例临床分析  

Clinical analysis on 526 children with Henoch-Schonlein purpura in eastern Guangdong

作　　者：张利滨 林明祥[1] 黄楚君[1] 麦隽[1] 李逸峰 袁慧霞 ZHANG Li-bin;LIN Ming-xiang;HUANG Chu-jun;MAI Jun;LI Yi-feng;YUAN Hui-xia(The Central Hospital of Shantou,Shantou 515000,China;Shantou University Medical College,Shantou 515000,China)

机构地区：[1]广东省汕头市中心医院,广东汕头155000 [2]东广省汕头大学医学院,广东汕头155000

出　　处：《广东医科大学学报》2020年第1期61-63,共3页Journal of Guangdong Medical University

基　　金：广东省医学科学技术研究基金(No.B2016136)

摘　　要：目的分析粤东地区儿童过敏性紫癜的临床特点。方法对526例过敏性紫癜患儿的一般资料、临床表现及实验室指标进行回顾性分析。结果526例患儿中,男女比例为1.4:1;发病年龄集中在2~8岁(占77.0%);发病季节主要集中在冬季,占40.9%;首发症状中表现为皮肤型者最多(占73.0%);年龄>8岁、复发和IgE升高是肾脏损害的独立危险因素。结论粤东地区过敏性紫癜多见于8岁以下儿童,且多发于冬季,其中肾脏损害与年龄、复发和IgE升高密切相关。Objective To analyze the clinical features of children with Henoch-Schonlein purpura(HSP)in eastern Guangdong.Methods The general data,clinical manifestation and laboratory indicators of 526 children with HSP were analyzed retrospectively.Results Among 526 sick children,the male to female ratio was 1.4:1,the age of onset mainly ranged from 2 to 8 years,accounting for 77.0%,and the onset seasons were mainly in winter,accounting for 40.9%;skin-type HSP(73.0%)was the initial symptoms that has been manifested the most;age of>8 years,recurrence and IgE elevation were independent risk factors for renal damage(P<0.05).Conclusion HSP in the eastern Guangdong is mainly found in children under 8 years old and frequently occurs in winter,and the HSP renal damage is closely related to age,recurrence and IgE elevation.

关 键 词：过敏性紫癜 临床特点 肾脏损害 复发 

分 类 号：R725[医药卫生—儿科]