静脉注射丙种球蛋白治疗早产儿肺炎临床疗效  

Clinical Efficacy of Intravenous Gamma Globulin in Premature Infants with Pneumonia

作　　者：于波[1] YU Bo(Department of Neonatal,Jiamusi Central Hospital,Jiamusi 154002,Heilongjiang,China)

机构地区：[1]佳木斯市中心医院新生儿科

出　　处：《医学信息》2020年第4期149-150,共2页Journal of Medical Information

摘　　要：目的分析静脉注射丙种球蛋白治疗早产儿肺炎临床疗效。方法选取2018年2月~2019年2月在我院治疗的早产儿肺炎54例,采用随机数字表法分为对照组和观察组,各27例。对照组采用常规治疗,观察组在对照组基础上给予静脉注射丙种球蛋白治疗,比较两组临床治疗总有效率、临床体征(体温恢复、呼吸频率正常、青紫缓解、啰音消失)改善时间、治疗前后血清免疫球蛋白G(IgG)水平以及临床并发症发生情况。结果观察组临床治疗总有效率为92.59%,高于对照组的81.48%(P<0.05);观察组体温恢复、呼吸频率正常、青紫缓解、啰音消失时间均短于对照组(P<0.05);治疗后两组IgG水平均高于治疗前,且观察组高于对照组(P<0.05);观察组并发症发生率为11.11%,低于对照组的25.92%(P<0.05)。结论静脉注射丙种球蛋白治疗早产儿肺炎临床疗效确切,有助于改善早产儿血清lgG水平,缓解临床症状,降低并发症发生率。Objective To analyze the clinical efficacy of intravenous gamma globulin in the treatment of premature infants with pneumonia.Methods 54 cases of pneumonia of premature infants treated in our hospital from February 2018 to February 2019 were selected and divided into a control group and an observation group with a random number table method,with 27 cases in each group.The control group received conventional treatment,and the observation group received intravenous gamma globulin therapy on the basis of the control group.The total effective rate of clinical treatment,recovery of clinical signs(temperature recovery,normal breathing rate,bluish cyanosis,disappearance of snoring sounds),serum immunoglobulin G(IgG)levels before and after treatment,and clinical complications were compared between the two groups.Results The total effective rate of clinical treatment in the observation group was 92.59%,which was higher than 81.48%in the control group(P<0.05).The time of body temperature recovery,normal breathing rate,bluish remission,and snoring disappearance in the observation group were shorter than those in the control group(P<0.05);the IgG levels of the two groups after treatment were higher than before the treatment,and the observation group was higher than the control group(P<0.05);the incidence of complications in the observation group was 11.11%,which was lower than 25.92%of the control group(P<0.05).Conclusion Intravenous injection of gamma globulin is effective in the treatment of pneumonia in preterm infants,and it is helpful to improve serum lgG levels in preterm infants,relieve clinical symptoms,and reduce the incidence of complications.

关 键 词：静脉注射丙种球蛋白 早产儿 肺炎 

分 类 号：R722.6[医药卫生—儿科]