我国药用海洋生物中重金属污染现状及检测、脱除技术研究进展  

Current situation of heavy metal pollution,detection and removal techniques in medicinal marine organisms in China

作　　者：孔丹丹 李歆悦 孟莹 骆骄阳[1] 杨世海[2] 杨美华[1] KONG Dan-dan;LI Xin-yue;MENG Ying;LUO Jiao-yang;YANG Shi-hai;YANG Mei-hua(Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine,Ministry of Education,Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100193,China;College of Traditional Chinese Medicine,Jilin Agricultural University,Changchun 130118,China)

机构地区：[1]中国医学科学院北京协和医学院药用植物研究所中草药物质基础与资源利用教育部重点实验室,北京100193 [2]吉林农业大学中药材学院,吉林长春130118

出　　处：《中国中药杂志》2019年第23期5022-5030,共9页China Journal of Chinese Materia Medica

基　　金：国家自然科学基金项目(81903797);中国医学科学院协同创新项目(2017-I2M-1-013,2016-I2M-3-010);协和青年基金资助和中央高校基本科研业务费专项资金(3332018201);国家重点研发计划项目(2018YFF0214202);国家重点研发计划中医药现代化研究项目(2018YFC1707900)

摘　　要：药用海洋生物作为传统药物的一个重要分支,其生物种类繁多,生物活性显著并且在抗肿瘤、抗病毒、抗凝血、镇痛抗菌以及心脑血管疾病等的治疗上有着突出的成效等优点。近年来,随着人类对海洋生物的不断探索,在其中还发现了许多具有特定生物活性和药用前景的海洋有机物,得到了世界各国的极大重视,并将药用海洋生物称作解决人类健康问题的"新希望"。然而,由于现代化工业的快速发展,重金属污染对药用海洋生物资源造成了极大的威胁,同时也阻碍了海洋生物医药行业的发展,威胁着人类健康。鉴于此,该文首先介绍了药用海洋生物发展趋势及重金属污染现状,重点阐述了适用于药用海洋生物中重金属的分析技术与化学脱除技术,以期为海洋药物中重金属及有害元素的控制和海洋药物的开发利用方面的研究提供参考。As an important branch of traditional medicines,medicinal marine organisms have many advantages,including biological diversity,remarkable biological activity,especial for the treatment of anti-cancer,anti-virus,anti-coagulation,analgesia,anti-bacterial,cardiovascular and cerebrovascular diseases. In recent years,with the continuous exploration of marine organisms by human beings,many marine organisms with specific biological activities and medicinal prospects have been found,which have attracted great attention around the world and thus called " new hope" to solve human health problems. However,due to the rapid development of modern industry,heavy metal pollution not only poses a great threat to medicinal marine living resources,but also hinders the development of marine biomedical industry and threatens human health. In view of this,this paper introduced the development trend of medicinal marine organisms and the current situation of heavy metal pollution and focusing on the analysis technology and chemical removal technology of heavy metals in medicinal marine organisms,which is to provide reference for the heavy metals control in marine medicines and the development and utilization of marine medicines.

关 键 词：药用海洋生物 重金属及有害元素 检测技术 脱除方法 

分 类 号：R284.1[医药卫生—中药学]