577nm激光光凝联合芪明颗粒治疗糖尿病视网膜病变Ⅲ期  

Clinical effect observation of 577nm laser photocoagulation combined with Qi Ming granule in patients with Ⅲ stage diabetic retinopathy

作　　者：潘昕[1] 白峰[1] 骆立夫[1] 张大光[2] Xin Pan;Feng Bai;Li-Fu Luo;Da-Guang Zhang(Department of Ophthalmology,the Second Hospital of Jilin University,Changchun 130041,Jilin Province,China;The First Hospital of Jilin University,Changchun 130021,Jilin Province,China)

机构地区：[1]吉林大学第二医院眼科,吉林省长春市130041 [2]吉林大学第一医院,吉林省长春市130021

出　　处：《国际眼科杂志》2020年第3期541-543,共3页International Eye Science

基　　金：吉林省中医药科技项目资助(No.2017092)~~

摘　　要：目的:探讨眼底激光联合芪明颗粒治疗糖尿病视网膜病变Ⅲ期的疗效观察。方法:将2017-12/2018-06在我院眼科需要行眼底激光治疗的56例糖尿病视网膜病变Ⅲ期患者随机分为两组:试验组(芪明颗粒联合眼底激光治疗)28例,对照组(眼底激光治疗)28例。观察两组治疗后视力(BCVA),平均视野缺损(MD),黄斑中心厚度(CMT)的改变,观察时间为6mo。结果:治疗后1、3、6mo试验组、对照组患眼平均BCVA、MD值、CMT值与治疗前比较均有差异(P<0.05)。治疗后1、3mo两组患眼平均BCVA、MD值、CMT值比较均有差异(P<0.05);治疗后6mo均无差异(P>0.05)。结论:芪明颗粒短期内可减轻激光光凝对视网膜功能损害程度,促使激光损伤的快速修复,减轻糖尿病性黄斑水肿。AIM:To explore the effect of fundus laser combined with Qi Ming granule on diabetic retinopathy in stage Ⅲ.METHODS:Fifty six patients with Ⅲ stage diabetic retinopathy who were treated in our hospital from December 2017 to June 2018 were divided into control group(28 cases)and observation group(28 cases)according to the treatment method.The control group was treated with panretinal photocoagulation.The observation group was treated with Qi Ming granule combined with retinal laser photocoagulation.The best-corrected visual acuity(BCVA),mean defect of visual field(MD),and central macular thickness(CMT)were examined before photocoagulation and 1mo,3mo and 6mo after photocoagulation to compare the retinal function between the two groups.RESULTS:The mean BCVA,MD and CMT values of the eyes in the PRP+drug treatment group and the PRP treatment group were statistically significant(P<0.05)at 1,3,and 6mo after treatment.The mean BCVA,MD and CMT values between the two groups were statistically significant(P<0.05)at 1 and 3mo after treatment.There was no significant difference at 6mo after treatment(P>0.05).CONCLUSION:Qi Ming granule can alleviate the degree of laser photocoagulation damage to the retina,promote the rapid repair of laser damage,and reduce diabetic macular edema.It is worthy of popularization and application in the clinic.

关 键 词：芪明颗粒 全视网膜激光光凝 糖尿病视网膜病变 黄斑水肿 

分 类 号：R587.2[医药卫生—内分泌] R779.63[医药卫生—内科学]