非新生儿破伤风诊疗规范  

Specifications for diagnosis and treatment of non-neonatal tetanus

作　　者：王传林[1] 刘斯[2] 陈庆军[3] 邵祝军[4] 吴纪峰[5] 范昭[6] 王培戈[7] 朱政纲[8] 兰频 李建国[10] 郑以山[11] 何武兵[12] 徐哲 唐卫东 逄金满[15] 班志红 杨树青 丁文涛[18] 郑希福 张齐龙[20] Wang Chuanlin;Liu Si;Chen Qingjun;Shao Zhujun;Wu Jifeng;Fan Zhao;Wang Peige;Zhu Zhenggang;Lan Pin;Li Jianguo;Zheng Yishan;He Wubing;Xu Zhe;Tang Weidong;Pang Jinman;Ban Zhihong;Yang Shuqing;Ding Wentao;Zheng Xifu;Zhang Qilong(Emergency Department/Trauma Center,Peking University People's Hospital,Beijing 100044,China;Department of Emergency,Peking University First Hospital,Beijing 100034,China;Emergency Department,Beijing Hepingli Hospital,Beijing 100013,China;National Institute for Communicable Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China;Surgical Department,Shijiazhuang Fifth Hospital,Shijiazhuang 050021,China;Emergency Department,Peking University Shenzhen Hospital,Shenzhen 518036,China;Emergency Department,Affiliate Hospital of Qingdao University,Qingdao 266003,China;Rabies Clinic,Wuhan Center for Disease Control and Prevention,Wuhan 430015,China;Department of Emergency,Lishui Hospital,Zhejiang University School of Medicine,Lishui 323000,China;Emergency Department,Hebe General Hospital,Shijiazhuang 050051,China;Department of Critical Care Medicine,Second Hospital of Nanjing,Nanjing 210003 China;Provincial Clinical Medical College,Fujian Medical University,Fuzhou 350001,China;Centre of Infectious Diseases,Fifth Medical Centre of PLA General Hospital,Beijing 100039,China;Department of Orthopedics,Suzhou Road Hospital,Xinjiang Autonomous Region People's Hospital,Urumqi 830000,China;Thyroid and Breast Surgery,Third Hospital of Jinan,Jinan 250132,China;Emergency Department,Guangxi International Zhuang Medicine Hospital,Nanning 530200,China;Emergency Department,Chongqing Emergency Medical Center/Central Hospital of Chongqing University,Chongqing 400014,China;Department of General Surgery,Tianjin First Central Hospital,Tianjin 300192,China;Department of Orthopedic Surgery,First Affiliated Hospital of Dalian Medical University,Dalian 116011,China;Department of Emergency and Critical Care Medicine,Jiangxi Chest Hospital,Nanchang 330006,China)

机构地区：[1]北京大学人民医院急诊科/创伤救治中心,100044 [2]北京大学第一医院急诊科,100034 [3]北京市和平里医院急诊科,100013 [4]中国疾病预防控制中心传染病预防控制所,北京102206 [5]石家庄市第五医院外科,050021 [6]北京大学深圳医院急诊科,518036 [7]青岛大学附属医院急诊科,266003 [8]武汉市疾病预防控制中心狂犬病门诊,430015 [9]浙江大学丽水医院急诊科,323000 [10]河北省人民医院急诊科石家庄,050051 [11]南京市第二医院重症医学科,210003 [12]福建医科大学省立临床医学院,福州350001 [13]解放军总医院第五医学中心感染性疾病诊疗与研究中心二科,北京100039 [14]新疆自治区人民医院苏州路院区骨科,乌鲁木齐830000 [15]济南市第三人民医院两腺外科,250132 [16]广西国际壮医医院急诊科,南宁530200 [17]重庆市急救医疗中心/重庆大学附属中心医院急诊部,400014 [18]天津市第一中心医院普通外科,300192 [19]大连医科大学附属第一医院骨科,116011 [20]江西省胸科医院急诊危重症医学科,南昌330006

出　　处：《中华创伤杂志》2020年第1期18-23,共6页Chinese Journal of Trauma

摘　　要：破伤风分为新生儿破伤风和非新生儿破伤风。我国已于2012年消除了新生儿破伤风,但非新生儿破伤风仍是一个严重的公共卫生问题。非新生儿破伤风重症患者若无医疗干预,病死率接近100%。即使经过积极的综合治疗,全球范围内非新生儿破伤风病死率仍为30%~50%,是一种极为严重的潜在致死性疾病。为规范我国非新生儿破伤风诊疗行为、提高医疗质量、保障医疗安全,特制定本规范。本规范包括非新生儿破伤风的病原学、流行病学、发病机制、临床表现及实验室检查、诊断、鉴别诊断、分级、治疗等方面内容。Tetanus consists of neonatal tetanus and non-neonatal tetanus.Non-neonatal tetanus remains a serious public health problem,although neonatal tetanus has been eliminated in China since 2012.Non-neonatal tetanus is a potential fatal disease.In the absence of medical intervention,the mortality rate of severe cases is almost 100%.Even with vigorous treatment,the mortality rate remains 30%-50%globally.These specifications aim to regulate non-neonatal tetanus diagnosis and treatment in China,in order to improve medical quality and safety.These specifications introduce the etiology,epidemiology,pathogenesis,clinical manifestations and laboratory tests,diagnosis,differential diagnosis,grading and treatment of non-neonatal tetanus.

关 键 词：破伤风 非新生儿 规范 诊断 治疗 

分 类 号：R722[医药卫生—儿科]