抗-cE及抗-Jk^b和抗-Mur混合抗体致疑难配血分析——附1例报告  

Analysis of theincompatibility in blood crossmatching induced by anti-cE,anti-Jk^b and anti-Mur antibodies

作　　者：杨红梅[1] 邹昕 郑皆炜[2] 向东 许飞[1] 曹锁春[1] 张建伟[1] YANG Hongmei;ZOU Xin;ZHENG Jiewei;XIANG Dong;XU Fei;CAO Suochun;ZHANG Jianwei(Changzhou Blood Center,Changzhou 213004,China;Shanghai Blood Center)

机构地区：[1]常州市中心血站,江苏常州213004 [2]上海市血液中心

出　　处：《中国输血杂志》2020年第1期70-72,共3页Chinese Journal of Blood Transfusion

基　　金：江苏省输血协会英科新创科研基金(JS2018037);常州市卫计委指导性课题(WZ201729)

摘　　要：目的探讨1例疑难交叉配血不合的原因。方法通过ABO血型鉴定、Rh分型、直接抗人球蛋白试验、不规则抗体筛查、抗体特异性鉴定及抗体效价测定对患者配血不合进行分析。结果对照谱细胞反应格局,患者血清中检出抗-cE、抗-Jk^b和抗-Mur。结论患者血清中不规则抗体是导致交叉配血不合的主要原因。Objective To investigate the reason of incompatibility caused by anti-cE combined with anti-Jk^b and anti-Mur antibodies in crossmatching. Methods ABO blood group identification, Rh typing, direct anti-human globulin test, irregular antibody screening, antibody specificity identification and antibody titer determination were used to analyze the matching incompatibility of patients. Results Anti-cE, anti-Jk^b and anti-Mur antibodies were detected in the serum of patients in control of the cell spectrum response pattern.Conclusion Theirregular antibodies in the serum of patients are the main cause of cross match mismatch.

关 键 词：交叉配血 抗体筛查 不规则抗体 抗-MUR 抗-JK^B 

分 类 号：R457.11[医药卫生—治疗学]