登革病毒实验室诊断方法研究进展  

Research progress of laboratory diagnostic methods of dengue virus

作　　者：巩沅鑫 郭红霞 叶楠 邱民月 杨茂成 李晋涛 GONG Yuan-xin;GUO Hong-xia;YE Nan;QIU Min-yue;YANG Mao-cheng;LI Jin-tao(Department of Military Biosafety,School of Basic Medical Sciences,Army Medical University,Chongqing 400038,China;Clinical laboratory,the 962 Hospital of The PLA Joint Logistic Support Force,Harbin 150080,China)

机构地区：[1]陆军军医大学基础医学院军事生物安全教研室,重庆400038 [2]中国人民解放军联勤保障部队第962医院检验科,哈尔滨150080

出　　处：《中华疾病控制杂志》2020年第1期85-89,共5页Chinese Journal of Disease Control & Prevention

基　　金：国家自然科学基金(81570497)~~

摘　　要：目前登革病毒(dengue virus, DENV)已被世界卫生组织视为热带及亚热带地区的重大公共卫生问题。近年来全球范围内登革热疫情频发,有愈演愈烈的趋势。仅2019年已在菲律宾、泰国、孟加拉国、缅甸及中国重庆市暴发了不同程度的登革热疫情。DENV的实验室诊断方法对于登革疫情的防控意义重大。为此本文对现阶段DENV实验室诊断方法及策略进行综述。通过回顾以往传统性诊断方法,展望新兴的诊断策略,为登革疫情暴发时选择合适的实验室诊断方案提供参考。Dengue virus(DENV)has been identified by World Health Organization as a major public health problem in tropical and subtropical regions.In recent years,dengue outbreaks have become more and more frequent in the world.In 2019,dengue outbreaks of varying degrees have occurred in the Philippines,Thailand,Bangladesh,Myanmar and Chongqing City in China.The laboratory diagnostic method of DENV is of great significance to the prevention and control of dengue epidemic.Therefore,the methods and strategies of DENV laboratory diagnosis are reviewed in this paper.By reviewing the traditional diagnostic methods and looking forward to the emerging diagnostic strategies,this paper aims to provide a reference to select the appropriate laboratory diagnostic scheme for the outbreak of dengue.

关 键 词：DENV 诊断 RNA转染 基因编辑技术 

分 类 号：R373.3[医药卫生—病原生物学]