氯诺昔康与舒芬太尼用于口腔颌面外科手术后自控镇痛的效果比较  

Comparison of the efficacy of lornoxicam and sufentanil in self-controlled analgesia after oral and maxillofacial surgery

作　　者：刘维娜 LIU Weina(General Operating Room,First Affiliated Hospital of Bengbu Medical College,Anhui Province,Bengbu City 233000,China)

机构地区：[1]安徽省蚌埠市医学院第一附属医院综合手术室

出　　处：《临床合理用药杂志》2019年第35期26-28,共3页Chinese Journal of Clinical Rational Drug Use

摘　　要：目的比较氯诺昔康与舒芬太尼用于口腔颌面外科手术(OMS)后自控镇痛(PCIA)的效果。方法回顾性分析医院收治的需行颌面外科手术患者80例临床资料,按术后所用阵痛药不同分为氯诺昔康组(40例)和舒芬太尼组(40例)。比较2组患者经PCIA治疗后不同时间点视觉模拟评分(VAS),采用镇静Ramsay评分法比较2组PCIA治疗后2、6、24、48 h评分,生活质量评分和术后不良反应发生情况。结果治疗后1、2周,氯诺昔康组VAS评分均低于舒芬太尼组(P <0. 01);治疗后6、24、48 h,氯诺昔康组Ramsay评分均优于舒芬太尼组(P <0. 01);治疗后,氯诺昔康组各个维度评分均明显高于治疗前,且高于舒芬太尼组(P <0. 01);氯诺昔康组不良反应发生率为5. 00%,低于舒芬太尼组的25. 00%(P <0. 05)。结论口腔颌面外科手术后行PCIA治疗,可减轻患者术后疼痛,提升预后生活质量,同时采用氯诺昔康阵痛效果更加显著,值得临床推广应用。Objective To compare the effects of lornoxicam and sufentanil on self-controlled analgesia( PCIA) after oral and maxillofacial surgery. Methods The clinical data of 80 patients who needed maxillofacial surgery were retrospectively analyzed. They were divided into lornoxicam group( 40 cases) and sufentanil group( 40 cases) according to different pain medications. Compare the visual analogue scores( VAS) of the two groups of patients at different time points after PCIA treatment. Sedation Ramsay score was used to compare the 2 nd,6 th,24 th,and 48 h scores after PCIA treatment in the two groups. The quality of life scores and postoperative adverse reactions were compared between the two groups. Results At 1 and 2 weeks after treatment,the VAS scores of the lornoxicam group were lower than those of the sufentanil group( P <0. 01). At 6,24,and 48 hours after treatment,the Ramsay score of the lornoxicam group was better than that of the sufentanil group( P < 0. 01). After treatment,the scores of the lornoxicam group in all dimensions were significantly higher than before the treatment,and higher than the sufentanil group( P < 0. 01). The incidence of adverse reactions in the lornoxicam group was 5. 00%,which was lower than 25. 00% in the sufentanil group( P < 0. 05). Conclusion Patients undergoing PCIA after oral and maxillofacial surgery can reduce pain,improve prognosis,and improve quality of life. At the same time,the effect of lornoxicam pain is more significant,which is worthy of clinical application.

关 键 词：氯诺昔康 舒芬太尼 口腔颌面外科手术 术后自控镇痛 

分 类 号：R614[医药卫生—麻醉学]