三磷酸腺苷在TiO2掺杂碳纳米纤维修饰电极上的电化学行为  

Electrochemical behavior of adenosine triphosphate on TiO2 doped carbon nanofiber modified electrode

作　　者：牛燕燕[1] 谢慧[1] 李小宝[1] 庄玉娇 阮承祥 孙伟[1] NIU Yanyan;XIE Hui;LI Xiaobao;ZHUANG Yujiao;RUAN Chengxiang;SUN Wei(Key Laboratory of Laser Technology and Optoelectronic Functional Materials of Hainan Province,Key Laboratory of Functional Materials and Photoelectrochemistry of Haikou,College of Chemistry and Chemical Engineering,Hainan Normal University,Haikou 571158;Jiangxi Key Laboratory of Surface Engineering,Material and Machinery Engineering,Jiangxi Science and Technology Normal University,Nanchang 330013)

机构地区：[1]海南师范大学化学与化工学院海南省激光技术与光电功能材料重点实验室海口市功能材料与光电化学重点实验室,海口571158 [2]江西科技师范大学材料与机电学院江西材料表面工程重点实验室,南昌330013

出　　处：《分析试验室》2020年第1期57-61,共5页Chinese Journal of Analysis Laboratory

基　　金：海南省自然科学基金创新研究团队项目(2017CXTD007);海口市重点科技计划项目(2017042)资助

摘　　要：采用循环伏安法和示差脉冲伏安法研究了三磷酸腺苷(ATP)在TiO2掺杂碳纳米纤维(TiO2@CNF)修饰的碳离子液体电极表面(TiO2@CNF/CILE)的电化学行为。结果表明,ATP在TiO2@CNF/CILE表面有一个明显的氧化峰,在pH 3.0的Britton-Robinson(BR)缓冲溶液中修饰电极对ATP具有显著的电催化作用。纤维状的TiO2@CNF能够有效促进电子转移,增加电化学信号。当ATP浓度分别在4.0×10^-9~2.0×10^-6mol/L和2.0×10^-6~1.0×10^-4mol/L范围时,氧化峰电流与ATP浓度呈良好的线性关系,检测限为1.4 nmol/L。修饰电极可用于注射液中ATP的测定。Electrochemical behavior of adenosine triphosphate(ATP)on the surface of TiO2 doped carbon nanofiber(TiO2@CNF)modified carbon ionic liquid electrode(TiO2@CNF/CILE)was studied by cyclic voltammetry and differential pulse voltammetry.The results showed that ATP had an obvious oxidation peak on TiO2@CNF/CILE.In pH 3.0 BR buffer solution,TiO2@CNF/CILE exhibited significant electrocatalytic effect to ATP oxidation.TiO2@CNF could effectively increase the electrochemical signal and promote electron transfer.The oxidation peak current increased with the ATP concentration in the range of 4.0×10^-9-2.0×10^-6 mol/L and 2.0×10^-6-1.0×10^-4 mol/L with detection limit of 1.4 nmol/L(3σ).The modified electrode could be used for the detection of ATP in injection sample with high sensitivity.

关 键 词：TiO2掺杂碳纳米纤维 三磷酸腺苷 电化学传感器 

分 类 号：R446[医药卫生—诊断学]