嗜线虫致病杆菌抗菌代谢产物Xcn1的研究进展  

The Research Progress of Secondary Metabolite Xcn1 in Xenorhabdus nematophila

作　　者：李广悦[1] 杨秀芬[1] LI Guangyue;YANG Xiufen(State Key Laboratory for Biology of Plant Diseases and Insect Pests/Institute of Plant Protection,Chinese Academy of Agricultural Sciences,Beijing 100193,China)

机构地区：[1]中国农业科学院植物保护研究所/植物病虫害生物学国家重点实验室

出　　处：《中国生物防治学报》2020年第1期1-8,共8页Chinese Journal of Biological Control

基　　金：国家自然科学基金(31972327)

摘　　要：Xenocoumacin1(Xcn1)是嗜线虫致病杆菌产生的一种水溶性小肽类抗菌化合物,对真菌和细菌具有广谱的抑菌活性,在农业病害防治中具有良好的开发和应用前景。本文综述了Xcn1化合物的合成和降解机制、合成调控机制、抗菌作用机制以及防控植物疫病的研究进展,并展望了高产Xcn1生产菌株的改良和产业化应用前景。Xenocoumacin1(Xcn1), a kind of water-soluble peptide antimicrobial compounds from Xenorhabdus nematophila, shows wide-spectrum antimicrobial activity towards bacteria and fungi, demonstrating great application potential in crop disease control. In this paper, we summarized the research progress of this compound in synthesis, degradation, regulation and crop disease control, and pointed out the possible strategies for strain engineering and industrial production.

关 键 词：嗜线虫致病杆菌 代谢产物 Xcn1 病害防控 

分 类 号：S476[农业科学—农业昆虫与害虫防治]