真菌漆酶：多样的生物学功能及复杂的天然底物  

Fungal Laccase: Multi-biofunction and Complicated Natural Substrates

作　　者：刘宁[1,3] 贾慧 申珅[1,3] 曹志艳 董金皋[1,2,3] LIU Ning;JIA Hui;SHEN Shen;CAO Zhi-Yan;DONG Jin-Gao(College of Life Sciences,Hebei Agricultural University,Baoding 071001,China;College of Plant Protection,Hebei Agricultural University,Baoding 071001,China;Hebei Key Laboratory of Physiological and Molecular Plant Pathology,Baoding 071001,China)

机构地区：[1]河北农业大学生命科学学院,保定071001 [2]河北农业大学植物保护学院,保定071001 [3]河北省植物生理与分子病理学重点实验室,保定071001

出　　处：《农业生物技术学报》2020年第2期333-341,共9页Journal of Agricultural Biotechnology

基　　金：国家玉米产业技术体系(CARS-02);河北省自然科学基金(C2018204059);国家自然科学基金(31901827)

摘　　要：漆酶是一种含有铜离子的多酚氧化酶,广泛存在于真菌、植物、细菌及昆虫中。在真菌中漆酶多以基因家族形式存在,编码的同工酶参与真菌形态建成、色素合成、侵染及致病等多种重要生物学过程。漆酶作用底物范围广泛,可以催化氧化包括多酚、芳香胺类及木质素等多种化合物。漆酶的研究主要集中于降解有毒有害物质、脱色等人工化合物的催化过程等方面,对其在生物体中天然催化底物及其参与的代谢途径的鉴别及分析研究较少。本文对漆酶在真菌中的生物学功能及其天然催化底物进行综述,以期为阐明漆酶发挥生物学功能的作用机制提供参考。Laccase is a polyphenol oxidase containing copper ions, which occur widely in fungi, plants,bacteria and insects. In fungi, laccases are generally in the form of gene families encoding isozymes which are involved in many important biological processes including fungal morphogenesis, pigment synthesis,infection and pathogenesis. Laccase catalyze the oxidation of a wide variety of substrates such as polyphenols,aromatic amines and lignin. However, the research about laccases mainly focuses on the degradation and decolorization of artificial compounds such as toxic compounds. There are few studies on the identification and analysis of natural catalytic substrates and their metabolic pathways in fungi. In this paper, the biological functions of fungal laccase and its natural catalytic substrate are reviewed to clarify the mechanism of laccase biological function.

关 键 词：真菌漆酶 生物功能 天然底物 

分 类 号：S43[农业科学—农业昆虫与害虫防治] Q71[农业科学—植物保护]