一次性宫腔压迫双球囊联合卡前列素氨丁三醇防治前置胎盘伴胎盘植入产后出血效果  

Efficacy observation of intraoperative application of disposable uterine cavity compression double balloon combined with carboprost tromethamine for preventing postpartum hemorrhage of women with placenta previa and placenta accreta

作　　者：卞桂萍[1] 薛艳春[1] 田亦平[1] BIAN Guiping;XUE Yanchun;TIAN Yiping(Jingjiang People’s Hospital,Jiangsu Province, 214500)

机构地区：[1]江苏省靖江市人民医院

出　　处：《中国计划生育学杂志》2020年第1期85-88,共4页Chinese Journal of Family Planning

摘　　要：目的:探讨一次性宫腔压迫双球囊联合卡前列素氨丁三醇防治前置胎盘伴胎盘植入患者产后出血的临床疗效。方法:选取前置胎盘伴胎盘植入患者64例,随机数字表方法分为两组(n=32),对照组术中应用卡前列素氨丁三醇,观察组在对照组基础上联合应用一次性宫腔压迫双球囊,比较两组产后出血情况。结果:观察组术中、产后2 h及24 h出血量均低于对照组,产后出血发生率(9.4%)低于对照组(40.6%)(均P<0.05);胎盘和子宫因素共同存在时子宫出血发生率更高(P<0.05);两组手术时间、新生儿Apgar评分比较无差异(P>0.05);观察组子宫切除术率、Blynch缝合术率、输血率和住院时间均低于对照组(P<0.05)。结论:前置胎盘伴胎盘植入患者在剖宫产术中联合应用一次性宫腔压迫双球囊与卡前列素氨丁三醇,能够有效预防产后出血,降低子宫切除风险,改善妊娠结局。Objective:To investigate the clinical efficacy of disposable uterine cavity compression balloon combined with carboprost tromethamine for preventing postpartum hemorrhage of women with placenta previa and placenta accreta.Methods:64 women with placenta previa and placenta accreta were randomly divided into two groups(32 cases in each group)by random numbers table.The women in the control group were treated by carboprost tromethamine,and the women in the observation group were treated by disposable uterine cavity compression double balloon combined with carboprost tromethamine.The postpartum hemorrhage situation of women was compared between the two groups.Results:The bleeding amount during operation,valumes of postpartum at 2 hours and 24 hours of women in the observation group were significant lower than those of women in the control group(P<0.05).The incidence of postpartum hemorrhage of women in the observation group was 9.4%,which was significant lower than that(40.6%)of women in the control group(P<0.05).The incidence of postpartum hemorrhage of women with mixing factor(placenta and uterine factor)was significant higher(P<0.05).There were no significant different in the operation time and Apgar scores of newborn between the two groups(P>0.05).The rates of hysterectomy,Blynch suture and blood transfusion,and hospitalization time of women in the observation group were significant lower than those of women in the control group(P<0.05).Conclusion:Intraoperative application of disposable uterine cavity compression double balloon combined with carboprost tromethamine for treating women with placenta previa and placenta accreta during cesarean can effectively prevent postpartum hemorrhage occurance,reduce the risk of hysterectomy,and can improve pregnancy outcomes.

关 键 词：前置胎盘 胎盘植入 产后出血 一次性宫腔压迫双球囊 卡前列素氨丁三醇 

分 类 号：R71[医药卫生—妇产科学]