Deciphering the metabolic fates of herbal constituents and the interactions of herbs with human metabolic system  

作　　者：GE Guang-Bo 

机构地区：[1]Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine

出　　处：《Chinese Journal of Natural Medicines》2019年第11期801-802,共2页中国天然药物（英文版）

基　　金：supported by the National Key Research and Development Program of China(No.2017YFC1700200)

摘　　要：Herbal medicines play a crucial role in the healthcare system in China and other East Asian countries,and also have been used as alternative medicines in most Western countries[1-3].However,in most cases,the metabolic fates of herbal constituents and their effects on drug metabolism or endogenous metabolism in the human body have not been well-investigated[4-5].Notably,the concomitant use of herbal medicines may lead to clinically relevant herb-drug interactions or adverse reactions or even metabolic disorders,when some herbs are co-administrated with those drugs with narrow therapeutic indices(e.g.warfarin,digoxin,thyroid hormones and some anticancer agents)[6-8].

关 键 词：HERBAL METABOLISM HERBS 

分 类 号：R285[医药卫生—中药学]