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作 者:杨云[1,2] 冯剑 朱杰霄[1] 刘洋洋 陈德力[1] 魏建和 YANG Yun;FENG Jian;ZHU Jie-xiao;LIU Yang-yang;CHEN De-li;WEI Jian-he(Hainan Provincial Key Laboratory of Resources Conservation and Development of Southern Medicine&Key Laboratory of State Administration of Traditional Chinese Medicine for Agarwood Sustainable Utilization,Hainan Branch of the Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences and Peking Union Medical College,Haikou 570311,China;Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine,Ministry of Education&National Engineering Laboratory for Breeding of Endangered Medicinal Materials,Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100193,China)
机构地区:[1]中国医学科学院北京协和医学院药用植物研究所海南分所,海南省南药资源保护与开发重点实验室,国家中医药管理局沉香可持续利用重点研究室,海口570311 [2]中国医学科学院北京协和医学院药用植物研究所,中草药物质基础与资源利用教育部重点实验室,濒危药材繁育国家工程实验室,北京100193
出 处:《中国药学杂志》2019年第23期1988-1994,共7页Chinese Pharmaceutical Journal
基 金:国家重点研发计划项目资助(2018YFC1706401);国家自然科学基金项目资助(81703660);国家中药材产业技术体系项目资助(CARS-21);中组部“万人计划”项目资助(99950534);中国医学科学院与健康科技创新工程项目资助(2016-I2M-2-003);海南省重点研发计划项目资助(ZDYEF2019218)
摘 要:目的比较中国及东南亚国家沉香树采用通体结香技术产沉香的质量异同。方法依据《中国药典》2015年版的沉香标准,分析和评价中国及东南亚国家11个产地的11批通体结香技术产沉香的性状、鉴别项、浸出物、含量测定、特征图谱,并测定总色酮类化合物含量。结果11批通体结香技术产沉香样品的形态特征、薄层色谱、特征图谱均相似,所有样品中均观察到木间韧皮部、导管和射线等特征结构;国内6个产地的通体结香技术产沉香的浸出物及总色酮类化合物含量均高于东南亚国家的5个产地。与其他人工结香方法产的沉香相比,通体结香技术产的沉香的感官特征较为稳定,浸出物及总色酮类化合物平均含量明显较高,但沉香四醇平均含量略低于外周结香和火烙法结香的沉香。结论从质量而言,通体结香技术优于传统结香方法,该技术不仅适用于中国的白木香树(Aquilaria sinensis)结香,也适用于东南亚国家的沉香树结香。通体结香技术产沉香的质量总体较优,但白木香树产的沉香质量优于东南亚树种产的沉香。OBJECTIVE To investigate the similarities and differences of the quality of agarwood produced by agar-wit from China and Southeast Asian countries.METHODS The sensory characteristic,identification item,extract,content determination,characteristic chromatogram and total chromone content of agarwood produced by agar-wit from 11 place of origins of China and Southeast Asian countries were mainly evaluated,according to the Chinese Pharmacopoeia(2015 edition).RESULTS The morphological characteristics,TLC and characteristic chromatograms of 11 batches of agarwood produced by agar-wit were similar.Special structures such as included phloem,vessel and rays were observed in all samples.The extract and total chromone contents of agarwood produced by agarwit from the six producing areas in China were higher than those from the five producing areas in Southeast Asia.Compared with other agarwood-inducing method,the sensory characteristics of the agarwood produced by agar-wit were relatively stable,and the average contents of the extract and total chromone were significantly higher,but the average content of agarotetrol was slightly lower than that of the agarwood produced by peripheral-inducing and iron-inducing.CONCLUSION In terms of quality,the agar-wit is superior to the traditional agarwood-inducing method.It is not only applicable to the agarwood production of Aquilaria sinensis in China,but also applicable to the species of Aquilaria Lam.in Southeast Asian countries.The quality of agarwood produced by agar-wit is good in general,but the quality of the agarwood produced by A.sinensis is better than the species of Aquilaria Lam.in the Southeast Asian.
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