阻断乙肝病毒母婴传播的研究进展  

Research progress on blocking mother-to-child transmission of Hepatitis B virus

作　　者：马丽娜[1] Ma Lina(Baoding City Center for Disease Control and Prevention,Baoding,Hebei 071000,China)

机构地区：[1]保定市疾病预防控制中心,河北保定071000

出　　处：《医药前沿》2019年第36期10-12,共3页Journal of Frontiers of Medicine

摘　　要：我国是乙型肝炎的高流行区,慢性乙型肝炎病毒(简称HBV)感染者约1.2亿人,大部分人群是通过母婴传播感染的,发展成为乙型肝炎病毒携带者、慢性肝炎患者、肝硬化患者、肝癌患者成为新的传染源.母婴传播在乙型肝炎流行中占十分重要的地位.预防新生儿HBV感染明显减少严重肝病的发生率,从而大大减轻社会和家庭的负担.几十年来,对乙型肝炎母婴传播的研究报道甚多,相关学者观点不尽相同.笔者查阅诸多文献对阻断乙肝母婴传播中如乙肝疫苗阻断;乙肝免疫球蛋白阻断;乙肝疫苗和乙肝免疫球蛋白联合阻断;乙肝抗病毒治疗等的研究进展进行综述.China is a high epidemic area of Hepatitis B,about 120 million people are infected with chronic Hepatitis B virus(HBV),most people are infected through mother-to-child transmission,it has developed into Hepatitis B virus carriers,chronic Hepatitis,cirrhosis and hepatocellular carcinoma new sources of infection.Mother-to-child transmission plays an important role in the epidemic of Hepatitis B.Preventing neonatal HBV infection significantly reduces the incidence of severe liver disease,thus greatly reducing the burden on society and families.For decades,there have been many reports on mother-to-child transmission of Hepatitis B,and most scholars have different opinions.The author consulted many literatures to block mother-to-child transmission of Hepatitis B,such as Hepatitis B vaccine alone,Hepatitis B immunoglobulin was blocked alone,The combined use of Hepatitis B vaccine and Hepatitis B immunoglobulin was blocked,The progress of anti-viral therapy for Hepatitis B is reviewed.

关 键 词：乙肝病毒 乙肝疫苗 乙肝免疫球蛋白 母婴传播 阻断 

分 类 号：R512.6[医药卫生—内科学]