普罗帕酮与胺碘酮急诊转复阵发性室上性心动过速及对心率变异性的影响观察  

Effects of propafenone and amiodarone on the emergency conversion of paroxysmal supraventricular tachycardia and heart rate variability

作　　者：刘发琼 吴金琼 Liu Faqiong;Wu Jinqiong(Department of Cardiology,the Traditional Chinese Medical Hospital of Fengjie County,Chongqing City,Chongqing,Fengjie,Chongqing 404699)

机构地区：[1]重庆市奉节县中医院心内科

出　　处：《中国社区医师》2020年第7期16-17,共2页Chinese Community Doctors

摘　　要：目的:观察胺碘酮和普罗帕酮治疗阵发性室上性心动过速(PSVT)的效果。方法:2017年4月-2019年4月收治PSVT患者68例,随机分为两组,各34例。观察组应用胺碘酮治疗,对照组应用普罗帕酮治疗。比较两组临床疗效、不良反应、复律成功率及心率变异性(HRV)。结果:两组总有效率及复律成功率比较,差异无统计学意义(P>0.05)。观察组HRV参数优于对照组,不良反应发生率低于对照组,差异均有统计学意义(P<0.05)。结论:胺碘酮和普罗帕酮治疗PSVT临床效果和复律成功率相近,但胺碘酮较普罗帕酮不良反应低,降低HRV参数效果更佳。Objective:To investigate the effect of amiodarone and propafenone on paroxysmal supraventricular tachycardia(PSVT).Methods:From April 2017 to April 2019,68 patients with PSVT were selected and randomly divided into two groups of 34 cases in each.Amiodarone was used in the observation group and propafenone was used in the control group.We compared the clinical efficacy,adverse reactions,success rate of cardioversion and heart rate variability(HRV)between the two groups.Results:There was no significant difference in total effective rate and successful rate of cardioversion between the two groups(P>0.05).In the observation group,HRV parameters were better than the control group,and the incidence of adverse reactions was lower than the control group,the difference was statistically significant(P<0.05).Conclusion:The effect and the success rate of cardioversion of amiodarone and propafenone in the treatment of PSVT is similar,however,compared with propafenone,the conversion rate of amiodarone is higher,and its adverse reactions are lower,the effect of reducing HRV parameters is better.

关 键 词：阵发性室上性心动过速 胺碘酮 普罗帕酮 转复 

分 类 号：R541.7[医药卫生—心血管疾病]