局部注射醋酸曲安奈德致迟发过敏反应1例  

A case of delayed allergic reaction caused by local injection of triamcinolone acetonide

作　　者：曾庆雯 彭思斯 白新娜 陈珺[1] 刘斌杰[1] 潘灏[1] ZENG Qingwen;PENG Sisi;BAI Xinna;CHEN Jun;LIU Binjie;PAN Hao(Department of Periodontics&Oral Mucosal Section,Xiangya Stomatological Hospital&Xiangya School of Stomatology&Hunan Key Laboratory of Oral Health Research,Central South University,Changsha 410008,China;Department of Conservative Dentistry&Endodontics,Xiangya Stomatological Hospital&Xiangya School of Stomatology&Hunan Key Laboratory of Oral Health Research,Central South University,Changsha 410008,China)

机构地区：[1]中南大学湘雅口腔医学院&湖南中南大学湘雅口腔医院&口腔健康研究湖南省重点实验室牙周科&黏膜科,长沙410008 [2]中南大学湘雅口腔医学院&湖南中南大学湘雅口腔医院&口腔健康研究湖南省重点实验室牙体牙髓科,长沙410008

出　　处：《中南大学学报（医学版）》2020年第2期216-220,共5页Journal of Central South University ：Medical Science

基　　金：湖南省卫生健康委员会研究基金(B20190104);中南大学研究生自主探索创新项目(2019zzts736);湘雅口腔医院和口腔医学院青年研究启动基金(B2018002)~~

摘　　要：糖皮质激素是临床上常用的抗炎、抗过敏药物。糖皮质激素过敏是一类由糖皮质激素作为变应原引起的过敏反应,在临床上并不多见,其超敏反应的临床表现无特异性。现报道1例湖南中南大学湘雅口腔医院收治的口腔扁平苔藓患者,在接受舌部局部注射醋酸曲安奈德后出现迟发性过敏反应。患者表现为舌部黏膜局部糜烂、出血、疼痛,予以双氯芬酸钠缓释片口服、碳酸氢钠注射液漱口、康复新液含服后过敏症状缓解。临床上需进一步加深对此类药物的认识,对考虑糖皮质激素过敏的患者需要尽快切断过敏原,并根据超敏反应类型进行相应的处理,从而改善治疗效果。Glucocorticoid is a commonly used anti-inflammatory and anti-allergic drug in clinic.Allergic reactions caused by glucocorticoids are rare in clinic. Glucocorticoid allergy is a type of allergic reaction caused by glucocorticoid as an allergen, and its clinical manifestations of hypersensitivity are not specific. Here we reported a case of an allergic reaction in patients with oral lichen planus who received submucosal injection of triamcinolone acetonide in the tongue. The patient showed local erosion, bleeding, and pain in the mucous membrane of the tongue in the Xiangya Stomatological Hospital, Central South University. The allergic symptoms were relieved after the patient was given diclofenac sodium sustained-release tablets, sodium bicarbonate injection for gargle, and Kangfuxin liquid.It is the clinical need to further deepen the understanding of glucocorticoid allergy. The allergens should be cut off as soon as possible, and the corresponding treatment is performed according to the type of hypersensitivity reaction, thereby improving the therapeutic effect.

关 键 词：糖皮质激素 过敏 口腔扁平苔藓 醋酸曲安奈德 

分 类 号：R593.1[医药卫生—内科学]