老年冠状动脉慢性完全闭塞患者经皮冠状动脉介入治疗的短期及长期结局  

Short-term and long-term outcomes of percutaneous coronary intervention in elderly patients with coronary chronic total occlusion

作　　者：邓德明[1] 林美明[1] 郑元琦[1] 陈曦 DENG De-ming;LIN Mei-ming;ZHENG Yuan-qi(Department of Cardiology,Sanming First Hospital,Sanming 353000,China)

机构地区：[1]福建省三明市第一医院心血管内科福建医科大学附属三明市第一医院心血管内科

出　　处：《中国现代药物应用》2020年第5期18-20,共3页Chinese Journal of Modern Drug Application

摘　　要：目的 研究老年冠状动脉慢性完全闭塞(CTO)患者行经皮冠状动脉介入治疗(PCI)的短期及长期结局。方法 128例行PCI的CTO患者,根据患者行PCI时的年龄分为非老年组(年龄<65岁,81例)和老年组(年龄65~75岁,47例)。分析比较两组患者一般资料、PCI相关指标及长期随访结果 。结果 老年组患者女性占比51.06%高于非老年组的32.10%,吸烟占比17.02%低于非老年组的38.27%,差异具有统计学意义(P<0.05)。两组患者高血压病、2型糖尿病及既往急性冠脉综合征占比比较,差异均无统计学意义(P>0.05)。非老年组和老年组患者的PCI成功率分别为81.48%和76.60%,比较差异无统计学意义(P>0.05);两组PCI操作期间及操作后30 d内均无患者死亡,未发生脑卒中及急诊CABG。两组严重出血、造影剂相关肾病发生率比较,差异无统计学意义(P>0.05)。随访期间,老年组患者中8例(17.02%)死亡,非老年组患者中12例(14.81%)死亡;两组患者死亡率比较,差异无统计学意义(P>0.05)。结论 老年CTO患者行PCI治疗可取得较高的成功率及与非老年患者类似的短期和长期结局,年龄不应成为阻碍老年CTO患者行PCI的因素。Objective To study the short-term and long-term outcomes of percutaneous coronary intervention(PCI)in elderly patients with coronary chronic total occlusion(CTO).Methods A total of 128 CTO patients with PCI were divided into non-elderly group(<65 years old,81 cases)and elderly group(65-75 years old,47 cases)according to the age of PCI.The general data,PCI related indicators and long-term follow up results were analyzed and compared between the two groups.Results The proportion of female patients in the elderly group was 51.06%,which was higher than 32.10%in non-elderly group,and the proportion of smoking was 17.02%,which was lower than 38.27%in non-elderly group.The difference was statistically significant(P<0.05).There was no statistically significant difference in proportion of hypertension,type 2 diabetes mellitus and previous acute coronary syndrome between the two groups(P>0.05).The PCI success rate was 81.48%and 76.60%in nonelderly group and elderly group,and the difference was not statistically significant(P>0.05).There was no death,stroke or emergency CABG in the two groups during and 30 d after PCI.There was no statistically significant difference in incidence of severe hemorrhage and contrast-related nephropathy between the two groups(P>0.05).During follow-up,8 patients(17.02%)died in the elderly group,and 12 patients(14.81%)died in the non-elderly group.There was no statistically significant difference in death rate between the two groups(P>0.05).Conclusion PCI in elderly CTO patients can achieve higher success rates and short-term and long-term outcomes similar to non-elderly patients.Age should not be a factor that prevents elderly CTO patients from undergoing PCI.

关 键 词：冠状动脉慢性完全闭塞 经皮冠状动脉介入治疗 预后 心血管介入 

分 类 号：R541.4[医药卫生—心血管疾病]