盐酸阿米替林片联合自拟中药汤剂治疗紧张型头痛的效果及安全性  

Effect and safety of Amitriptyline Aydrochloride Tablets combined with self-made traditional Chinese medicine decoction in the treatment of tension-type headache

作　　者：连捷[1] 杨宇峰[2] LIAN Jie;YANG Yu-feng(Department of Encephalopathy,the Second People′s Hospital of Dalian,Liaoning Province,Dalian116000,China;Laboratory Center,Liaoning University of Traditional Chinese Medicine,Liaoning Province,Dalian110032,China)

机构地区：[1]大连市第二人民医院脑病科,辽宁大连116000 [2]辽宁中医药大学实验中心,辽宁大连110032

出　　处：《中国当代医药》2020年第5期170-172,共3页China Modern Medicine

摘　　要：目的探讨盐酸阿米替林片联合自拟中药汤剂治疗紧张型头痛的效果及安全性。方法选取大连市第二人民医院2017年3月~2019年3月收治的150例紧张型头痛患者为研究对象,按照随机数字表法分为干预组(75例)和对照组(75例),对照组采用盐酸阿米替林片治疗方法,干预组采用盐酸阿米替林片联合自拟中药汤剂治疗方法。比较两组的治疗效果、头痛程度及不良反应发生情况。结果干预组治疗总有效率高于对照组,差异有统计学意义(P<0.05);干预组治疗后头痛程度及不良反应总发生率均低于对照组,差异有统计学意义(P<0.05)。结论盐酸阿米替林片联合自拟中药汤剂治疗能减轻紧张型头痛患者头痛程度,提高治疗效果,且安全性高。Objective To investigate the effect and safety of Amitriptyline Hydrochloride Tablets combined with self-made traditional Chinese medicine decoction in the treatment of tension-type headache.Methods A total of 150 patients with tension-type headache who were admitted to the Second People′s Hospital of Dalian from March 2017 to March 2019 were enrolled.The patients were divided into intervention group(75 cases)and control group(75 cases)according to the random number table method.The control group was treated with Amitriptyline Hydrochloride Tablets,and the intervention group was treated with Amitriptyline Hydrochloride Tablets and self-made traditional Chinese medicine decoction.The effect of treatment,headache and adverse reactions were compared between the two groups.Results The total effective rate of treatment in the intervention group was higher than that in the control group,and the difference was statistically significant(P<0.05).The degree of headache and total adverse reaction rate in the intervention group were lower than those in the control group,the differences were statistically significant(P<0.05).Conclusion The combination of Amitriptyline Hydrochloride Tablets and self-made traditional Chinese medicine decoction can alleviate the headache degree of patients with tension-type headache,improve the therapeutic effect,and has high safety.

关 键 词：盐酸阿米替林片 自拟中药汤剂 紧张型头痛 安全性 

分 类 号：R245[医药卫生—针灸推拿学]