丙泊酚、依托咪酯和乳化异氟烷诱导对乳化异氟烷维持麻醉犬效果及心电图的影响  

Anesthetic effects and electrocardiogram in dogs following induction using propofol,etomidate or emulsified isoflurane,and emulsified isoflurane maintenance anaesthesia

作　　者：刘超 徐彤彤 王铭真 戴雨薇 周振雷[1] LIU Chao;XU Tongtong;WANG Mingzhen;DAI Yuwei;ZHOU Zhenlei(College of Veterinary Medicine,Nanjing Agricultural University,Nanjing 210095,China;College of Food Science and Technology,Nanjing Agricultural University,Nanjing 210095,China)

机构地区：[1]南京农业大学动物医学院,江苏南京210095 [2]南京农业大学食品科技学院,江苏南京210095

出　　处：《南京农业大学学报》2020年第2期292-299,共8页Journal of Nanjing Agricultural University

基　　金：江苏高校优势学科建设工程资助项目

摘　　要：[目的]本文旨在评价丙泊酚、依托咪酯静脉诱导对犬乳化异氟烷持续输注的麻醉效果和心电图的影响。[方法]5只犬接受3种诱导麻醉(丙泊酚、依托咪酯和乳化异氟烷分别诱导)管理,每个处理间隔2周。诱导麻醉后以8%乳化异氟烷(8 mL·kg^-1·h^-1)维持麻醉。监测各项生理指标、心电图和麻醉效果并评分。[结果]3种诱导方法均诱导迅速,起效快。在乳化异氟烷维持过程中脉搏血氧饱和度均较低,在90%左右。丙泊酚诱导引起P波升高和T波加深;依托咪酯诱导引起S-T段显著延长和T波左右不对称;乳化异氟烷诱导导致S-T段延长,且有斜型上移。[结论]丙泊酚、依托咪酯和乳化异氟烷均有良好的诱导效果。在乳化异氟烷维持麻醉状态下对心电图均有不同程度的影响。[Objectives]The paper aimed to investigate the effect of propofol,etomidate or emulsified isoflurane induced anaesthesia on anaesthesia,and electrocardiogram(ECG)results during emulsified isoflurane maintenance anaesthesia.[Methods]5 dogs received each of 3 incluced treatments(propofol,etomidate or emulsified isoflurane)with at least 2 weeks between treatments.After induced anaesthesia,the dogs followed by 8%emulsified isoflurane to maintain anaesthesia.The physiological indicators anaesthesia effect and ECG were monitored and evaluated score.[Results]The results showed that all the three induction methods provided good conditions for the induction of anaesthesia and acted quickly.Pulse oxygen saturation(SpO 2)was lower to about 90%in all groups during emulsified isoflurane maintenance anaesthesia.The P-wave and T-wave increased in propofol group;the etomidate caused significant extension of the S-T segment and T-wave asymmetry;the S-T segment was deviation and extension in the emulsified isoflurane group.[Conclusions]Propofol,etomidate or emulsified isoflurane have good inducted effects.They have different effects in ECG when emulsified isoflurane is used to maintain anesthesia.

关 键 词：犬 心电图 乳化异氟烷 丙泊酚 依托咪酯 诱导麻醉 

分 类 号：S857.12[农业科学—临床兽医学]