盐酸坦索罗辛治疗输尿管下段结石的临床疗效观察  

Clinical study of Tamsulosin on patients with lower ureteral calculi

作　　者：洪怀山[1] 黄美霞[2] 刘志华[1] 周志鹏[1] 叶烈夫[1] Hong Huaishan;Huang Meixia;Liu Zhihua(The Provincial Clinical Medical College of Fujian Medical University,Fujian Provincial Hospital,Fujian Provincial Jinshan Hospital,Fuzhou,Fujian 350001;The School of Pharmacy of Fujian Traditional Chinese Medicine University,Fuzhou,Fujian 350108)

机构地区：[1]福建医科大学省立临床医学院,福建省立医院,福建省立金山医院,福建福州350001 [2]福建中医药大学药学院,福建福州350108

出　　处：《基层医学论坛》2020年第4期465-467,共3页The Medical Forum

摘　　要：目的探讨盐酸坦索罗辛治疗输尿管下段结石的临床疗效。方法将86例输尿管下段结石患者随机分成试验组43例与对照组43例,试验组予盐酸坦索罗辛联合尿石通治疗,对照组单用尿石通治疗。比较2组患者的排石总有效率、止痛药使用率及药物不良反应发生情况。结果试验组与对照组排石总有效率分别为95.34%(41/43)和79.07%(34/43),差异有统计学意义(P<0.05)。试验组与对照组止痛药使用率分别为16.28%(7/43)和37.21%(16/43),差异有统计学意义(P<0.05)。2组均未出现严重药物不良反应。结论盐酸坦索罗辛治疗输尿管下段结石临床疗效确切,安全性高。Objective To evaluate the clinical effect of tamsulosin in the treatment for lower ureteral calculi.Methods A total of 86 patients with lower ureteral calculi were divided into group treatment and control group,43 cases in each group.Patients in treatment group were treated with Tamsulosin and Niao Shi Tong Wan.Patients in control group were given Niao Shi Tong Wan.The clinical efficacy,use of analgesics for renal cramps and adverse drug reactions of two groups were compared.Results The clinical efficacy in treatment group was 95.34%(41/43),had significant difference with that in control group,which was79.07%(34/43)(P<0.05).The use of analgesics for renal cramps in treatment group was 16.28%(7/43),had significant difference with that in control group,which was37.21%(16/43)(P<0.05).There was no significant adverse drug reaction in two groups.Conclusion The tamsulosin in the treatment of lower ureteral calculi was effective with high safety.

关 键 词：输尿管下段结石 盐酸坦索罗辛 疗效 安全性 

分 类 号：R693.4[医药卫生—泌尿科学]