Are claudin-5 tight-junction proteins in the blood-brain barrier porous?  

作　　者：David Fisher Shireen Mentor 

机构地区：[1]Department of Medical Biosciences,University of the Western Cape,Bellville,Cape Town,South Africa [2]School of Health Professions,University of Missouri,Columbia,MO,USA

出　　处：《Neural Regeneration Research》2020年第10期1838-1839,共2页中国神经再生研究（英文版）

摘　　要：The capillaries of the brain are particularly special,as they are not simply conduits for blood,but are primarily responsible to ensure that the neurons function in a strictly regulated homeostatic interstitium.Brain endothelial cells(BECs)express a plethora of ion channels on its luminal and abluminal surfaces,namely:potassium(K^+)channels(i.e.,Kir2 and Kv1),chloride(Cl^)/bicarbonate(HCO3^–)channels,as well as a number of ion-solute exchangers(Redzic et al.,2011).

关 键 词：POROUS POTASSIUM SOLUTE 

分 类 号：R338[医药卫生—人体生理学]