妊娠高血压病血脂与红细胞压积水平特点及其对妊娠结局的影响研究  

Characteristics of serum lipid and hematocrit in pregnancy-induced hypertension and its effect on pregnancy outcome

作　　者：杨旭[1] 齐俊巧[1] 郭丽魁[1] 范春燕[1] 路春梅[1] YANG Xu;Qi Jun-qiao;GUO Li-kui(Department of Obstetrics,Qin Huangdao First Hospital,Qin Huangdao 066000,China)

机构地区：[1]秦皇岛市第一医院产科,河北秦皇岛066000

出　　处：《中国实验诊断学》2020年第2期254-256,共3页Chinese Journal of Laboratory Diagnosis

摘　　要：目的探讨不同发病程度妊高症患者血脂相关指标(TC、TG、LDL、apo-A1、apo-B)与红细胞压积(HCT)水平特点及其对患者妊娠结局产生的影响。方法将180例我院妇产科收治的妊高症按照疾病发病程度分为妊娠高血压组(n=50)、轻度子痫前期组(n=50)、重度子痫前期组(n=60)以及子痫孕妇组(n=20)。同时,选取同期于我院接受检查的100例健康孕妇作为对照组。采用HITACHI全自动生化分析仪(型号为7600型)对上述各组入选对象血脂指标进行检测,采用Sysmex KX-21型血液分析仪对HCT水平进行检测。对比上述各组相关指标水平。结果 (1)妊高症各组患者相关血脂指标(TC、TG、LDL、apo-A1、apo-B)水平均分别显著高于对照组(P均<0.05),且随着发病程度地加重,上述指标水平也随之而上升;妊高症各组患者HDL及HCT水平均显著低于对照组(P均<0.05),且随着发病程度地加重,上述指标水平也随之而下降;(2)对照组妊娠结局显著优于妊高症组(P均<0.05)。结论妊高症会对孕产妇妊娠结局产生不良影响,该病会引起血脂及红细胞压积等指标的变化。Objective To investigate the effects of blood lipid-related indicators(TC,TG,LDL,apo-A1,apo-B)on hematocrit(HCT)levels in patients with pregnancy-induced hypertension at different levels of onset and their effects on pregnancy outcomes.Methods 180 cases of pregnancy-induced hypertension admitted to our department of obstetrics and gynecology were divided into pregnancy-induced hypertension group(n=50),mild pre-eclampsia group(n=50),and severe pre-eclampsia group(n=60)and the group of pregnant women with eclampsia(n=20).At the same time,100 healthy pregnant women who were examined in our hospital during the same period were selected as the control group.The HITACHI automatic biochemical analyzer(model 7600)was used to detect the blood lipid indexes of the selected groups,and the HCT level was detected by the Sysmex KX-21 blood analyzer.Compare the relevant indicator levels of the above groups.Results (1)The levels of blood lipids(TC,TG,LDL,apo-A1,apo-B)in the patients with pregnancy-induced hypertension were significantly higher than those in the control group(P<0.05),and the degree of disease Exacerbation,the above indicators also increased;the levels of HDL and HCT in patients with pregnancy-induced hypertension were significantly higher than those in the control group(P<0.05),and the level of these indicators decreased with the severity of the disease.(2)The pregnancy outcome of the control group was significantly better than that of the pregnancy-induced hypertension group(P<0.05).Conclusion Pregnancy-induced hypertension can have adverse effects on maternal outcomes,which can cause changes in blood lipids and hematocrit.

关 键 词：妊高症 血脂 红细胞压积 妊娠结局 

分 类 号：R714.246[医药卫生—妇产科学]