三发性甲状旁腺功能亢进症诊治进展  

Progress in diagnosis and treatment of tertiary hyperparathyriodism

作　　者：张妍妍 王培松[1] 王雪薇 陈光[1] Zhang Yanyan;Wang Peisong;Wang Xuewei;Chen Guang(Department of Thyroid Surgery,the First Hospital of Jilin University,Changchun 130021,China)

机构地区：[1]吉林大学第一医院甲状腺外科,130000

出　　处：《中华内分泌外科杂志》2020年第1期83-86,共4页Chinese Journal of Endocrine Surgery

基　　金：吉林省科技厅自然科学基金项目(20180101138JC)。

摘　　要：甲状旁腺功能亢进(hyperparathyriodism,HPT)依据其发病原因不同可分为3种类型:原发性、继发性、三发性甲状旁腺功能亢进。一些患者在长期的继发性甲旁亢(secondary hyperparathyroidism,SHPT)的基础上,因甲状旁腺受到长期持久的刺激,增生的腺体有了自主功能,发展成能自主性的分泌甲状旁腺素(parathyroid hormone,PTH)的结节,称之为三发性甲状旁腺功能亢进(tertiary hyperparathyroidism,THPT)。以往国内对于三发性甲旁亢的报道相对较少见,可能与临床医生的认识及经验不足有关。随着国内外肾移植病例的增多,其发病率也呈现逐渐增加的趋势。THPT是影响慢性肾衰竭患者死亡率和生活质量的严重并发症,故加深对THPT的认识,规范内科药物治疗,严格把握手术指征,选择个体化手术方案尤为重要。According to the cause of hyperparathyriodism(HPT),it can be divided into three types:primary hyperparathyroidism(PHPT),secondary hyperparathyroidism(SHPT)and tertiary hyperparathyroidism(THPT).THPT is a state of excessive autonomous excretion of parathyroid hormone(PTH)after longstanding SHPT.In the past,reports of THPT is relatively rare in domestic,which may be related to the understanding and experience of clinicians.With the increase of kidney transplant cases all over the word,the incidence rate has also gradually increased.Therefore,it is especially important to deepen the knowledge of THPT,standardize the medical treatment,and strictly control the indications for surgery.

关 键 词：三发性甲状旁腺功能亢进症 肾移植 

分 类 号：R653[医药卫生—外科学] R736.1[医药卫生—临床医学]