低体质量对体外受精-胚胎移植妊娠结局的影响  

Impact of Low Body Mass on IVF-ET Outcome

作　　者：许月明[1] 张杰[1] 尹力 罗卓野 郝桂敏[1] XU Yue-ming;ZHANG Jie;YIN Li;LUO Zhuo-ye;HAO Gui-min(Department of Reproductive Medicine,The Second Hospital of Hebei Medical University,Shijiazhuang 050000,China)

机构地区：[1]河北医科大学第二医院生殖医学科,石家庄050000

出　　处：《国际生殖健康／计划生育杂志》2020年第2期101-103,共3页Journal of International Reproductive Health/Family Planning

摘　　要：目的:旨在评估低体质量对中国女性体外受精-胚胎移植(IVF-ET)新鲜周期妊娠率及活产率的影响。方法:回顾性研究2013年1月-2018年10月于河北医科大学第二医院生殖中心首次接受IVF/胞浆内单精子注射(ICSI)助孕的新鲜周期共8171个周期。其中,低体质量组[体质量指数(BMI)<18.5 kg/m^2]共774个周期,正常体质量组(BMI 18.5~23.9 kg/m^2)共7397个周期。结果:低体质量组患者的生化妊娠率和种植率低于正常体质量组(均P<0.05),但2组的临床妊娠率、流产率、活产率、早产率和足月产率比较,差异均无统计学意义(均P>0.05)。结论:低体质量可能对人类辅助生殖技术(ART)新鲜周期的妊娠结局存在负面影响。Objective: To evaluate the effects of low body mass index(BMI) on in vitro fertilization-embryo transfer(IVF-ET) outcomes in fresh transfer cycles. Methods:A total of 8 171 cycles with conventional stimulation and fresh transfer in our IVF/ICSI center from January 2013 to October 2018 were included. Patients with BMI<18.5 kg/m^2 were considered to be underweight(n=774), and patients with normal BMI(18.5-23.9 kg/m^2)were used as the control(n=7 397). Results:The biochemical pregnancy rate and implantation rate of the low BMI group were significantly lower than those of the control group(P<0.05). There were no significant differences in the clinical pregnancy rate, early abortion rate and live birth rate between the two groups(P>0.05). Conclusions:Low BMI is a negative factor of ART fresh transfer cycles.

关 键 词：低体重 人体质量指数 体外受精 胚胎移植 妊娠率 活产 

分 类 号：R714.8[医药卫生—妇产科学]