LED红蓝光照射联合异维A酸胶囊、夫西地酸乳膏治疗面部寻常型痤疮的疗效评价  

Efficacy evaluation of LED red and blue light combined with isotretinoin capsule and fusidic acid cream in the treatment of facial acne vulgaris

作　　者：陈婷婷 赖应庭[1] 张林香 谢四荣 丘毅龙 CHEN Ting-ting;LAI Ying-ting;ZHANG lin-xiang;XIE Si-rong;QIU Yi-long(Department of Dermatology,No.2 Hospital,Longyan City,Fujian Province,364000,China)

机构地区：[1]福建省龙岩市第二医院皮肤科,福建龙岩364000

出　　处：《中国医疗美容》2020年第1期28-31,共4页China Medical Cosmetology

摘　　要：目的探究LED红蓝光照射联合异维A酸胶囊、夫西地酸乳膏治疗面部寻常型痤疮的效果。方法 选取我院2017年10月至2019年4月面部寻常型痤疮患者76例,进行回顾性分析,根据治疗方案不同分为研究组(n=38)、对照组(n=38),对照组给予夫西地酸乳膏联合异维A酸胶囊,研究组在对照组基础上给予LED红蓝光照射,比较两组治疗效果、治疗前后皮损评分、治疗不同阶段临床症状改善程度(GAGS评分)、不良反应。结果研究组治疗总有效率97.37%(37/38)高于对照组78.95%(30/38)(P<0.05);治疗2个月后两组皮损评分均有所下降,且研究组低于对照组(P<0.05);治疗2周、1个月、2个月研究组GAGS评分均低于对照组(P<0.05);两组不良反应发生率比较无明显差异(P>0.05)。结论 LED红蓝光照射联合异维A酸胶囊、夫西地酸乳膏治疗面部寻常型痤疮效果确切,可有效改善临床症状,安全性高。Objective To investigate the effect of LED red and blue irradiation combined with isotretinoin capsules and fusidic acid cream on facial acne vulgaris.Methods 76 patients with facial acne vulgaris from October 2017 to April 2019 in our hospital were randomly divided into study group (n=38) and reference group (n=38).The reference group was given Fuxidi.Acid cream combined with isotretinoin capsules,the study group gave LED red and blue light on the basis of the reference group,comparing the treatment effect of the two groups,the lesion score before and after treatment,the improvement of clinical symptoms at different stages (GAGS score),and adverse reactions.Results The total effective rate of the study group was 97.37% (37/38) higher than that of the reference group (78.95% (30/38)) (P<0.05).After 2 months of treatment,the lesion scores of both groups decreased,and the study group was low.In the reference group (P<0.05);the GAGS scores of the study group were lower than the reference group at 2 weeks,1 month,and 2 months (P<0.05);the incidence of adverse reactions in the study group was 21.05% (5/38) and the reference.There was no significant difference in the group of 15.79% (2/38) (P>0.05).Conclusion LED red and blue light combined with isotretinoin capsules and fusidic acid cream can treat facial acne vulgaris effectively,which can effectively improve clinical symptoms and safety.

关 键 词：面部寻常型痤疮 夫西地酸乳膏 异维A酸胶囊 LED红蓝光照射 

分 类 号：R758.733[医药卫生—皮肤病学与性病学]