某三甲医院131例次输血不良反应回顾性分析  

Retrospective analysis of 131 case-times of blood transfusion adverse reactions in a class 3A hospital

作　　者：吴李萍[1] 罗敏[1] 李红霞 WU Liping;LUO Min;LI Hongxia(Department of Blood Transfusion,Chengdu Municipal First People's Hospital,Chengdu,Sichuan 610041,China)

机构地区：[1]四川省成都市第一人民医院输血科,四川成都610041

出　　处：《检验医学与临床》2020年第6期724-727,共4页Laboratory Medicine and Clinic

基　　金：四川省卫生和计划生育委员会课题(18PJ125)。

摘　　要：目的分析该院近4年输血不良反应的发生情况和患者的输注效果,为临床输血安全性和有效性管理提供依据。方法回顾该院2015-2018年《输血不良反应反馈单》及相关记录,分析输血不良反应的分布情况和特点,收集相关数据分析发生输血不良反应患者的输注效果。结果2015-2018年共输血35363例次,发生输血不良反应131例次,总发生率为0.37%,输血不良反应发生率呈逐年下降趋势。各年龄段人群均有输血不良反应发生,随年龄增长呈先上升后下降趋势;女性患者输血不良反应发生率明显高于男性(P<0.05)。输血不良反应主要为发热反应和过敏反应,分别占57.25%和38.17%。不同血液成分输血不良反应发生率以血小板最高,为0.78%,悬浮红细胞次之,为0.41%。悬浮红细胞输血不良反应发生例次随自体血回输增多而逐年递减。输注同样剂量悬浮红细胞和血小板,病例组输注效果均明显差于对照组(P<0.05)。结论该院输血不良反应发生率逐年降低,自体血回输对减少悬浮红细胞输血不良反应有一定作用。临床工作中应严格把握血液成分输注指征,持续开展并扩大自体输血覆盖面,保障临床科学、合理、安全用血。Objective To analyze the occurrence situation of blood transfusion adverse reactions in recent 4 years and the transfusion effect of the patients to provide a basis for the safety and the effective management of blood transfusion.Methods The Feedback Forms of Blood Transfusion Adverse Reaction and related records from 2015 to 2018 were conducted the retrospective analysis on the distribution situation and characteristics of blood transfusion adverse reactions,and the related data were collected for investigating the blood transfusion effect in the patients with blood transfusion adverse reactions.Results During 2015-2018,there were 35363 case-times of blood transfusion in this hospital.A total of 131 case-times of blood transfusion adverse reactions occurred with a total incidence rate of 0.37%,the incidence rate of blood transfusion adverse reactions showing a decreasing trend year by year.The transfusion adverse reaction occurred in the patients with various age groups,which showed an upward at first and then downward trend.The occurrence rate of blood transfusion adverse reactions in the female patients were significantly higher than that in the male patients(P<0.05).The febrile reaction and allergic reaction were the main types of blood transfusion adverse reaction,accounting for 57.25% and 38.17% respectively.Among different blood components,the incidence rate of blood transfusion adverse reactions was the highest in platelet(0.78%),followed by suspended red blood cells(0.41%).The adverse reaction case-times of suspended red blood cell transfusion showed a decreasing trend year by year with the increasing of autologous blood transfusion.The effects of same dosage of suspended red blood cell and platelet transfusion in the case group were significantly poorer than those in the control group(P<0.05).Conclusion The incidence rate of blood transfusion adverse reactions in this hospital is decreased year by year.The autologous blood transfusion has a certain effect on reducing the adverse reactions of suspended r

关 键 词：输血不良反应 发热反应 过敏反应 输注效果 

分 类 号：R457.13[医药卫生—治疗学]