叶酸、维生素B12、瑞舒伐他汀对冠心病合并高脂血症患者联合治疗价值分析  

The value of folic acid,vitamin B12 and rosuvastatin in the treatment of coronary heart disease with hyperlipidemia

作　　者：帅晔 SHUAI Ye(Taizhou People's Hospital,Jiangsu Taizhou 225300,China)

机构地区：[1]泰州市人民医院,江苏泰州225300

出　　处：《临床医药文献电子杂志》2019年第93期1-1,3,共2页Electronic Journal of Clinical Medical Literature

摘　　要：目的 研究维生素B12、叶酸和瑞舒伐他汀联合治疗冠心病合并高脂血症的临床疗效。方法 选取2017年1月~2019年1月在我院治疗的104例患者作为研究对象,将他们随机均分为两组,即对照组和观察组,两组各52例。对照组采取口服瑞舒伐他汀钙治疗,观察组在对照组的基础上结合维生素B12和叶酸联合治疗,比较两组患者治疗的总有效率和治疗后血脂指标。结果 观察组治疗的总有效率为98.08%高于对照组的86.54%;观察组患者治疗后的血脂指标优于对照组,两组比较差异皆具有统计学意义,P<0.05。结论 维生素B12、叶酸和瑞舒伐他汀结合治疗高血脂症合并冠心病疗效显著,值得临床借鉴。Objective To study the clinical efficacy of vitamin B12,folic acid and rosuvastatin in the treatment of coronary heart disease with hyperlipidemia.Methods 104 patients treated in our hospital from January 2017 to January 2019 were randomly divided into two groups:control group and observation group,52 cases in each group.The control group was treated with oral rosuvastatin calcium,while the observation group was treated with vitamin B12 and folic acid on the basis of the control group.The total effective rate and blood lipid index were compared between the two groups.Results The total effective rate of the observation group was 98.08%higher than 86.54%of the control group,and the blood lipid index of the observation group was better than that of the control group after treatment,the difference between the two groups was statistically significant(P<0.05).Conclusion The combination of vitamin B12,folic acid and rosuvastatin is effective in the treatment of hyperlipidemia with coronary heart disease,which is worthy of clinical reference.

关 键 词：叶酸 维生素B12 瑞舒伐他汀 冠心病合并高脂血症 

分 类 号：R541.4[医药卫生—心血管疾病]