珠海市2015-2018年性病门诊男性就诊者淋球菌与生殖道沙眼衣原体感染危险因素分析  

Risk factors for Neisseria gonorrhoeae and genital Chlamydia trachomatis infections among male outpatients attending sexually transmitted disease clinic in Zhuhai city,2015-2018

作　　者：陈伟 韦宁 黄弦 CHEN Wei;WEI Ning;HUANG Xian(Zhuhai Center for Chronic Disease Prevention&Treatment,Zhuhai,Guangdong 519000,China)

机构地区：[1]珠海市慢性病防治中心,广东珠海519000

出　　处：《实用预防医学》2020年第3期296-299,共4页Practical Preventive Medicine

基　　金：珠海市医学科研基金项目(20181117A010056);“广东省淋病及衣原体感染主动监测”项目资助。

摘　　要：目的了解珠海市性病门诊男性就诊者淋球菌(Neisseria gonorrhoeae,NG)和生殖道沙眼衣原体(genital Chlamydia trachomatis,GCT)感染现状及其危险因素,为针对该人群开展干预防治工作提供科学依据。方法2015-2018年每年4-6月,结合艾滋病哨点监测工作,以珠海市慢性病防治中心性病门诊男性就诊者为研究对象,开展问卷调查和血样、尿样检测。结果共有764例就诊者被纳入研究,平均年龄(36.73±12.02)岁,其中已婚者占比62.96%(481/764),广东省内户籍88.74%(678/764)。NG和GCT感染检测阳性率分别为1.83%(14/764)和6.15%(47/764),HIV和梅毒检测阳性率分别为2.23%(17/764)和11.65%(89/764)。logistic回归分析显示,注射过毒品是NG感染的危险因素(OR=27.19,95%CI:2.32~319.03,P<0.001);近3个月与临时性伴发生性行为(OR=2.44;95%CI:1.19~4.98),以及有与同性发生肛交性行为(OR=2.76;95%CI:1.23~6.24),是GCT感染的危险因素。此外,尿液白细胞异常与NG以及GCT感染均呈正相关,感染者与非感染者相比,白细胞异常占比更高,其OR值分别为49.63和12.32。结论2015-2018年珠海市性病门诊男性就诊者中的NG和GCT感染率均较高,作为性病防控最可及的人群,应加大对该人群的高危行为干预工作,提高性病防控工作成效。Objective To investigate the prevalence and risk factors of Neisseria gonorrhoeae(NG)and genital Chlamydia trachomatis(GCT)infections in male patients attending sexually transmitted disease(STD)clinic in Zhuhai city,and to provide a scientific basis for conducting intervention and prevention work in this population.Methods Based on HIV sentinel surveillance,male patients attending STD clinic of Zhuhai Center for Chronic Disease Prevention&Treatment from April to June each year during 2015-2018 served as the research subjects,and then questionnaire survey and detection of blood and urine samples were conducted.Results A total of 764 outpatients were enrolled in this study,and their average ages were(36.73±12.02)years.The married patients accounted for 62.96%(481/764),and the Cantonese patients 88.74%(678/764).The positive rates of NG,GCT,HIV and syphilis infection were 1.83%(14/764),6.15%(47/764),2.23%(17/764)and 11.65%(89/764),respectively.Logistic regression analysis showed that having ever injected drugs was the risk factor for NG infection(OR=27.19,95%CI=2.32-319.03,P<0.001).Having sex with temporary sexual partners in the past three months(OR=2.44,95%CI=1.19-4.98)and having anal sex with men(OR=2.76,95%CI=1.23-6.24)were the risk factors for GCT infection.In addition,urinary leukocyte abnormality was positively correlated with NG and GCT infections.The proportion of urinary leukocyte abnormality was higher in outpatients with NG infection than in ones without NG infection(OR=49.63)as well as higher in outpatients with GCT infection than in ones without GCT infection(OR=12.32).Conclusions The infection rates of NG and GCT were high among male outpatients in the STD clinic in Zhuhai city in 2015-2018.It is necessary to strengthen high-risk behavior intervention among male outpatients in the STD clinic,who are considered as the most accessible population for STD prevention and control,and improve the effectiveness of STD prevention and control.

关 键 词：淋球菌 生殖道沙眼衣原体 性病门诊 男性就诊者 

分 类 号：R759[医药卫生—皮肤病学与性病学]