健脾益气方药治疗I度直肠前突临床观察  

Clinical Observation of Prescription for Invigorating Spleen and Nourishing Qi in the Treatment of I Degree Rectocele

作　　者：唐雪松 于永铎[2] 王琳[1] TANG Xue-song;YU Yong-duo;WANG Lin(Liaoning University of TCM,Shenyang,Liaoning,China,110032;Third Affiliated Hospital of Liaoning University of TCM,Liaoning Hospital of TCM,Shenyang,Liaoning,China,110032)

机构地区：[1]辽宁中医药大学,辽宁沈阳110032 [2]辽宁中医药大学附属第三医院,辽宁省中医院,辽宁沈阳110032

出　　处：《河南中医》2020年第1期96-99,共4页Henan Traditional Chinese Medicine

基　　金：辽宁省中央引导地方科技发展专项项目(2017108007)。

摘　　要：目的:观察健脾益气方药治疗Ⅰ度直肠前突(rectocole,RC)的临床疗效。方法:将60例Ⅰ度直肠前突女性患者随机分为对照组和观察组各30例,对照组予枸橼酸莫沙必利片治疗,每次5 mg,日3次,饭前服用,观察组予补脾益气方药治疗,日1剂,每剂饮片煎药机煎煮两次,混合共为400 mL,早晚各1袋,口服。两组均连续治疗4周。治疗结束后观察两组患者排便困难、排便时间延长、排便不尽感、排粪造影影像学检查、气虚乏力症状以及患者的HAMD和HAMA评分情况。结果:治疗2周后,对照组患者排便困难、排便时间及排便不尽感评分与治疗前比较差异有统计学意义(P<0.01),组间比较有统计学意义(P<0.05)。治疗4周后,两组患者主要症状及排粪造影评分差异无统计学意义(P>0.05)。治疗2周后和4周后,观察组患者排粪造影评分和患者气虚、乏力症状评分与治疗前比较差异有统计学意义(P<0.01),而对照组与治疗前比较差异无统计学意义(P>0.05)。治疗后,两组患者HAMD、HAMA评分较治疗前均明显减少(P<0.01),且组间比较差异有统计学意义(P<0.01)。对照组有效率为83.33%,观察组有效率为93.33%,两组有效率比较,差异有统计学意义(P<0.05)。结论:补脾益气方药治疗Ⅰ度RC疗效显著,可缩小直肠前突距离,改善脾虚症状,减轻患者的焦虑和抑郁程度。Objective:To observe the clinical curative effect of Prescription for Invigorating Spleen and Nourishing Qi on I degree rectocel.Methods:A total of 60 cases of female patients with I degree rectocele were randomly divided into the control group and the observation group,with 30 cases in each group.The control group was treated with Mosapride Citrate Tablets,5 mg each time,3 times a day,taken before meals.The observation group was treated with Prescription for Invigorating Spleen and Nourishing Qi,1 dose a day,decocting twice with decocting machine for each decoction.The mixture was 400 mL,one bag in the morning and one bag in the evening.Both groups were treated continuously for 4 weeks.After the treatment,the patients′ difficulty in defecation,prolonged defecation time,incomplete defecation,image examination of defecography,symptoms of qi deficiency and fatigue,and HAMD and HAMA scores in the two groups were observed Results:After 2 weeks of treatment,there were significant differences in defecation difficulty,defecation time and defecation incompetence score in the control group between before and after treatment(P<0.01),and there were also significant differences between the two groups(P<0.05).After 4 weeks of treatment,there were no significant differences in the main symptoms and defecography scores between the two groups(P>0.05).After 2 and 4 weeks of treatment,there were significant differences in defecography score,Qi deficiency and fatigue symptom score the observation group between before and after treatment(P<0.01),while there were no significant differences in the control group between before and after treatment(P>0.05).After the treatment,the scores of HAMD and HAMA in the two groups were significantly lower than those before the treatment(P<0.01),and there was a significant difference between the two groups(P<0.01).The effective rate was 83.33% in the control group and 93.33% in the observation group.There was a significant difference between the two groups(P<0.05).Conclusion:Prescription for Invi

关 键 词：Ⅰ度直肠前突 补脾益气方药 HAMD HAMA 

分 类 号：R259.746.3[医药卫生—中西医结合]