针刺治疗糖尿病肢体动脉硬化闭塞症60例  

Sixty Cases of Diabetic Arteriosclerosis Obliterans Treated with Acupuncture Therapy

作　　者：相胜敏[1] 赵诚[1] 曹烨民[1] 刘笑迎[1] XIANG Sheng-min;ZHAO Cheng;CAO Ye-min;LIU Xiao-ying(Shanghai Integrated Traditional Chinese and Western Medicine Hospital,Shanghai,China,200082)

机构地区：[1]上海市中西医结合医院,上海200082

出　　处：《河南中医》2020年第1期123-125,共3页Henan Traditional Chinese Medicine

基　　金：上海市虹口区“国医强优”三年行动计划(2018-2020);中医药科研基金项目(HGY-KY-2018-29);上海市卫生和计划生育委员会项目(2016LQ010)。

摘　　要：目的:观察针刺治疗糖尿病肢体动脉硬化闭塞症(diabetic arteriosclerosis obliterans,DLASO)的临床疗效及其对患者白细胞介素-6(interleukin-6,IL-6)、C反应蛋白(C reactive protein,CRP)的影响。方法:将120例DLASO患者按照随机数字表法分为观察组和对照组,每组各60例。对照组给予控制血糖、抗感染、纠正低蛋白血症等综合疗法及创面清洁换药,观察组在对照组基础上给予针刺治疗。比较两组患者治疗前后临床症状积分及视觉模拟评分法(VAS)评分变化情况,检测两组患者治疗前后经皮氧分压、踝肱指数(ankle brachial index,ABI)、IL-6及CRP水平。结果:观察组有效率为93.33%,对照组有效率为75.00%,两组患者有效率比较,差异具有统计学意义(P<0.05)。两组患者治疗后临床症状积分、CRP、IL-6水平低于本组治疗前,且观察组低于对照组,差异具有统计学意义(P<0.05)。两组患者治疗后经皮氧分压、ABI高于治疗前,VAS评分低于治疗前,且观察组治疗后经皮氧分压、ABI高于对照组,VAS评分低于对照组,差异均有统计学意义(P<0.05)。结论:针刺疗法可改善DLASO患者的临床症状,降低炎性因子水平。Objective:To observe the clinical curative effect of acupuncture therapy on diabetic arteriosclerosis obliterans(DLASO) and its influence on interleukin-6(IL-6)C reactive protein(CRP).Methods:A total of 120 patients with DLASO were divided into the observation group and the control group according to the method of random number table,with 60 cases in each group.The control group was given comprehensive treatment such as control of blood sugar,anti infection,correction of hypoproteinemia and wound cleaning and dressing change.The observation group was additionally given acupuncture treatment on the basis of the control group.The improvement of clinical symptoms and the change of VAS scores before and after the treatment were compared between the two groups.The levels of transcutaneous oxygen partial pressure,ankle brachial index(ABI),IL-6 and CRP levels were measured before and after the treatment.Results:The effective rate was 93.33% in the observation group and 75.00% in the control group.The difference was statistically significant(P<0.05).After the treatment,TCM syndrome score,the levels of CRP and IL-6 in the two groups were lower than those before the treatment,and all the differences were statistically significant(P<0.05).After the treatment,the two groups′ transcutaneous oxygen partial pressure and ankle brachial index were higher than those before the treatment;the score of VAS was lower than that before the treatment.The transcutaneous oxygen partial pressure and ankle brachial index in the observation group were higher than those in the control group,while the score of VAS in the observation group was higher than that in the control group,and all the differences were statistically significant(P<0.05).Conclusion:Acupuncture can improve the clinical symptoms of DLASO patients and reduce the level of inflammatory factors.

关 键 词：糖尿病肢体动脉硬化闭塞症 针刺疗法 经皮氧分压 踝肱指数 白细胞介素-6 C反应蛋白 

分 类 号：R259.435[医药卫生—中西医结合]