An Open Invitation to Join the International Brugada Electrocardiographic Indices Registry  

作　　者：Gary Tse Sharen Lee Xuan Jiang Dong Chang Yunfei Gu Zhengrong Huang Xintao Li Qunshan Wang Shaoying Zeng Guoliang Li Dan Hu Jiandong Zhou Qingpeng Zhang Gan-Xin Yan Yunlong Xia Fang Zhou Liu Tong Liu 

机构地区：[1]Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease,Department of Cardiology,Tianjin Institute of Cardiology,Second Hospital of Tianjin Medical University,300211 Tianjin,China [2]Xiamen Cardiovascular Hospital,Xiamen University,Xiamen,361000 Fujian,China [3]Department of Cardiology,The First Affi liated Hospital of Dalian Medical University,Dalian,116000 Liaoning,China [4]Laboratory of Cardiovascular Physiology,Li Ka Shing Institute of Health Sciences,Hong Kong Special Administrative Region,China [5]Department of Cardiology,Guangdong Cardiovascular Institute,Guangdong Provincial People’s Hospital,Guangdong Academy of Medical Sciences,Guangzhou,510000 Guangdong,China [6]Department of Cardiology,Luoyang Central Hospital Affi liated to Zhengzhou University,Luoyang,471009 Henan,China [7]Department of Cardiology,The First Affi liated Hospital of Xiamen University,Xiamen,361000 Fujian,China [8]Department of Cardiology,The First People’s Hospital of Changzhou,Changzhou,213000 Jiangsu,China [9]Department of Cardiology,Xinhua Hospital,School of Medicine,Shanghai Jiao Tong University,200000 Shanghai,China [10]Guangdong General Hospital,No.106 Zhongshan 2nd Road,Yuexiu District,Guangzhou,510080 Guangdong,China [11]Arrhythmia Unit,Department of Cardiovascular Medicine,First Affi liated Hospital of Xi’an Jiaotong University,No.277 Yanta West Road,Xi’an,710000 Shaanxi,China [12]Department of Cardiology and Cardiovascular Research Institution,Renmin Hospital of Wuhan University,Wuhan,430000 Hubei,China [13]School of Data Science,City University of Hong Kong,Hong Kong Special Administrative Region,China [14]Lankenau Institute for Medical Research,Wynnewood,PA 19096,USA

出　　处：《Cardiovascular Innovations and Applications》2020年第1期217-221,共5页心血管创新与应用（英文）

摘　　要：Background:The Brugada Electrocardiographic Indices Registry is a comprehensive data registry composed of patients with Brugada patterns on the electrocardiogram(ECG).The aim is to test the hypotheses that(i)ECG indices combining both depolarization and repolarization abnormalities can better predict spontaneous ventricular arrhythmias than existing ECG markers in Brugada syndrome and(ii)that serial ECG measurements will provide additional information for risk stratifi cation,especially in asymptomatic patients.Methods:Patients with both Brugada pattern ECGs and Brugada syndrome are eligible for inclusion in this registry.Baseline characteristics and ECG variables refl ecting depolarization and repolarization will be determined.The primary outcome is spontaneous ventricular tachycardia/ventricular fi brillation or sudden cardiac death.Secondary outcomes are inducible ventricular tachycardia/ventricular fi brillation and syncope.Results:As of November 15,2019,39 investigators from 32 cities in 18 countries had joined this registry.As of December 15,2019,1383 cases had been enrolled.Conclusions:The Brugada Electrocardiographic Indices Registry will evaluate the disease life course,risk factors,and prognosis in a large series of Brugada patients.It will therefore provide insights for improving risk stratification.

关 键 词：SUDDEN cardiac death BRUGADA syndrome risk stratification ELECTROCARDIOGRAM indices BEIR CONSORTIUM 

分 类 号：R54[医药卫生—心血管疾病]