亚急性皮肤型红斑狼疮误诊为寻常性银屑病1例并文献复习  

Subacute Cutaneous Lupus Erythematosus Misdiagnosed as Psoriasis Vulgaris:A Case Report and Literature Review

作　　者：张素敏 魏洁丽 张禁 易松柏 杨颜龙 ZHANG Sumin;WEI Jieli;ZHANG Jin;YI Songbai;YANG Yanlong(Centeral Hospital of Xianning,Xianning 437100,China;Department of Dermatology,the 195 Hospital of Chinese People’s Liberation Army,Rehabilitation Center of Army Dermatology,Xianning 437100,China)

机构地区：[1]咸宁市中心医院湖北科技学院附属第一医院放射科,湖北咸宁437100 [2]湖北省咸宁市解放军195医院皮肤科,全军皮肤病康复中心,湖北咸宁437100

出　　处：《中国皮肤性病学杂志》2020年第2期236-238,共3页The Chinese Journal of Dermatovenereology

摘　　要：患者女,53岁,全身出现红色斑块、鳞屑反复发作15年,再发半年余,曾诊断为"湿疹"及"银屑病",效果欠佳。左前臂皮损组织病理示:表皮角化过度,基底细胞灶性液化变性,真皮全层血管及附属器周围可见淋巴细胞为主的炎症细胞浸润。免疫学示:ANA(+)、抗SSA抗体(+)、抗SSB抗体(-)、抗ds-DNA抗体(-)。诊断:亚急性皮肤型红斑狼疮(丘疹鳞屑型)。使用小剂量糖皮质激素、硫酸羟氯喹口服,糖皮质激素外搽,疗效明显。A 53-year-old female patient presented erythroid plaque and scales repeatedly around the whole body for 15 years,which was relapsed for more than half a year.The patient was effect.Histopathological examination of left forearm tissue showed epidermis hyperkeratosis,focal liquefaction and degeneration of basal cells,and lymphocytebased inflammatory cell infiltration around the whole dermal vessels and appendages.Immunological examination revealed ANA(+),anti-SSA antibody(+),anti-SSB antibody(-),and anti-ds-DNA antibody(-).The diagnosis was subacute cutaneous lupus erythematosus(papular scaly type).Low-doses of oral glucocorticoid and hydroxychloroquine sulfate were administered combined with external application of corticosteroid,which was effective.

关 键 词：红斑狼疮 亚急性 皮肤型 误诊 银屑病 

分 类 号：R593.24[医药卫生—内科学]