经鼻高流量湿化氧疗对急性心源性肺水肿患者的临床疗效  

Efficacy of high flow nasal cannulae therapy for acute cardiogenic pulmonary edema

作　　者：张国英[1] 王静[1] 王传霞[2] 张玄 迟翔宇[1] 李青[1] ZHANG Guoying;WANG Jing;WANG Chuanxia;ZHANG Xuan;CHI Xiangyu;LI Qing(Department of Geriatric Respiratory Disease,Shandong Provincial Hospital Affiliated to Shandong University,Jinan 250021,Shandong,China;Department of Geriatric Disease,Shandong Provincial Hospital Affiliated to Shandong University,Jinan 250021,Shandong,China;Postdoctoral Mobile Station of Shandong University of Traditional Chinese Medicine,Jinan 250000,Shandong,China)

机构地区：[1]山东大学附属省立医院老年呼吸科,山东济南250021 [2]山东大学附属省立医院老年医学科,山东济南250021 [3]山东中医药大学博士后流动站,山东济南250000

出　　处：《山东大学学报（医学版）》2020年第1期77-80,86,共5页Journal of Shandong University:Health Sciences

摘　　要：目的分析经鼻高流量湿化氧疗对急性心源性肺水肿患者的临床疗效。方法选取2018年10月1日至2019年8月1日于山东大学附属省立医院老年呼吸科因急性心源性肺水肿住院患者14例为治疗组,给予高流量湿化氧疗,分析临床疗效。另外选取同期于山东大学附属省立医院老年呼吸科住院并给予常规氧疗的心源性肺水肿患者12例作为对照组,对比两组患者呼吸频率、血氧饱和度、呼吸困难指数(mMRC)、舒适度等指标。结果治疗组患者均达到有效的临床控制,心源性肺水肿得到有效治疗,症状及体征好转,氧合指数上升(P=0.048)。与对照组比较治疗组患者0.5、1 h时呼吸频率、心率及mMRC较低,6 h时心率较低, 12 h时呼吸频率、心率较低, 24 h时心率较低。结论经鼻高流量湿化氧疗对急性心源性肺水肿患者有明确的临床疗效。Objective To explore the clinical efficacy of high flow nasal cannulae(HFNC) therapy for patients with cardiogenic pulmonary edema. Methods A total of 14 patients with cardiogenic pulmonary edema treated with HFNC therapy during ist Oct. 2018 and ist Aug. 2019 were selected as the treatment group, and another 12 patients with cardiogenic pulmonary edema who received routine oxygen therapy during the same period served as the control group. The respiratory rate, blood oxygen saturation, comfort and other indicators of the two groups were compared. Results All patients in the treatment group achieved effective clinical control, pulmonary edema was effectively treated, symptoms and signs were improved, and oxygenation indexes were increased(P=0.048). Compared with control group, treatment group had lower 0.5 h, 1 h and 12 h respiratory rate;lower 0.5 h, 1 h, 6 h, 12 h and 24 h heart rate;and lower 1 h mMRC. Conclusion HFNC therapy is effective in the treatment of cardiogenic pulmonary edema.

关 键 词：经鼻高流量湿化氧疗 心源性肺水肿 临床疗效 

分 类 号：R563[医药卫生—呼吸系统]