体素内不相干运动在腹部恶性肿瘤中的应用进展  

Research Progress of Intravoxel Incoherent Motion in Abdominal Malignant Tumors

作　　者：周婷婷 张继 田为中 ZHOU Tingting;ZHANG Ji;TIAN Weizhong(Department of Radiology,the Fifth Affiliated Hospital of Nantong University/Taizhou People's Hospital,Taizhou 225300,China)

机构地区：[1]南通大学第五附属医院泰州市人民医院医学影像科,江苏泰州225300

出　　处：《医学综述》2020年第5期904-908,914,共6页Medical Recapitulate

基　　金：江苏省青年医学重点人才课题(QNRC2016509);江苏省高层次卫生人才“六个一工程”拔尖人才科研项目(LGY2018032);江苏省卫生健康委员会科研项目(H2018093)。

摘　　要：传统的磁共振扩散加权成像(DWI)基于单指数模型计算评估组织中水分子的扩散情况,但组织中水分子运动情况不仅仅包括水分子扩散,且受微循环灌注的影响,故DWI不能反映组织中水分子运动的真实信息。磁共振体素内不相干运动(IVIM)扩散加权成像技术基于双指数模型可同时获得组织中水分子扩散及微循环灌注的信息,从而更能真实地反映组织中水分子运动。腹部恶性肿瘤大多血供较丰富,微循环灌注影响较大,故IVIM所提供的相关信息更能准确反映病变区的真实情况。Traditional magnetic resonance diffusion-weighted imaging(DWI)is based on a mono-exponential model to estimate the diffusion of water molecules in tissues,however,the movement of water molecule in tissues includes not only the diffusion of water molecule,but also the influence of microcirculation perfusion,so DWI can’t reflect the real information of water molecule movement in tissue.Intravoxel incoherent motion(IVIM)DWI can obtain both information about water molecule diffusion and microcirculation perfusion in tissue based on bi-exponential model,therefore,it can reflect the movement of water molecule in tissues more accurately.Most of the abdominal malignant tumors have abundant blood supply,and the influence of microcirculation perfusion is greater.Therefore,the information provided by the IVIM DWI can reflect the real situation of the lesion more accurately.

关 键 词：腹部恶性肿瘤 体素内不相干运动 扩散加权成像 单双指数模型 

分 类 号：R445.2[医药卫生—影像医学与核医学]