TNF-α拮抗剂治疗复发性疱疹样脓疱病一例  

Recurrent impetigo herpetiformis treated with TNF-α antagonist:a case report

作　　者：王娟娟 苏玉华[1] 丁瑜洁[1] 冷红[1] 季江[1] 施辛[1] WANG Juanjuan;SU Yuhua;DING Yujie;LENG Hong;JI Jiang;SHI Xin(Department of Dermatology,the Second Affiliated Hospital of Soochow University,Suzhou 215004,China)

机构地区：[1]苏州大学附属第二医院皮肤科,苏州215004

出　　处：《中国麻风皮肤病杂志》2020年第3期171-173,共3页China Journal of Leprosy and Skin Diseases

基　　金：国自然青年科学基金项目(编号:81803127);苏州市民生科技项目(编号:SS201643);苏州市科技发展计划(编号:SYS2018056)。

摘　　要：患者,女,31岁。妊娠期反复脓疱加重1个月。患者8年前妊娠期曾全身出现红斑、脓疱,产后皮损自行消失。根据患者既往病史、症状、体征及辅助检查,诊断"疱疹样脓疱病",入院后予TNF-α拮抗剂皮下注射,辅以复方甘草酸苷、阿奇霉素抗炎及外用药治疗,1周后患者皮疹明显好转出院。A 31-years-old female patient presented with widespread erythema and pustules during pregnancy,aggravating for 1 month.The patient had a history of the similar symptoms during pregnancy before 8 years ago and the lesions disappeared spontaneously after delivery.According to the patient s previous medical history,symptoms,physical signs and laboratory examination,the diagnosis of“impetigo herpetiformis”was made.The patient was injected subcutaneously with TNF-α antagonist,supplemented with Minol,Azithromycin anti-inflammatory and topical medication.The lesion was significantly improved after one week treatment.

关 键 词：疱疹样脓疱病 TNF-α拮抗剂 

分 类 号：R758.66[医药卫生—皮肤病学与性病学]