间断与持续蓝光照射应用于新生儿黄疸治疗中临床效果分析  

Clinical Effect Analysis of Intermittent and Continuous Blue Light Irradiation in the Treatment of Neonatal Jaundice

作　　者：陈国策 CHEN Guo-ce(Wuhan Children's Hospital,Wuhan,Hubei Province,430014 China)

机构地区：[1]武汉儿童医院,湖北武汉430014

出　　处：《中外医疗》2020年第1期75-77,共3页China & Foreign Medical Treatment

摘　　要：目的研究蓝光间断照射与持续照射应用于新生儿黄疸治疗中的治疗效果及患儿治疗过程中的不良反应发生情况。方法该研究方便选取该院收治的黄疸新生儿50例为对象,其就诊时间为2017年6月—2019年1月,患儿入院后均使用常规方式进行治疗,之后使用蓝光照射完成对患儿的治疗,根据患儿蓝光照射治疗方法的不同将其分为对照组和试验组,各25例,其中对照组患使用持续蓝光照射治疗,试验组患儿使用间断蓝光照射治疗,两组患儿均持续治疗3~5 d后结束。对两组患儿的治疗效果进行评价及比较,观察并比较两组患儿不良反应发生率,并比较两组患儿治疗前后的胆红素水平。结果两组患儿治疗总有效率比较,试验组96.00%的治疗总有效率高于对照组76.00%的治疗总有效率,差异有统计学意义(χ^2=4.153,P=0.042)。试验组患儿12.00%的不良反应发生率低于对照组的36.00%,差异有统计学意义(χ^2=3.947,P=0.047)。试验组患儿治疗前的胆红素平均水平为(271.95±45.28)μmol/L,治疗后平均胆红素水平为(134.29±24.17)μmol/L,治疗后与治疗前比较明显更低,差异有统计学意义(t=8.481,P=0.000)。对照组患儿治疗前的胆红素平均水平为(269.43±48.09)μmol/L,治疗后平均胆红素水平为(141.27±21.39)μmol/L,治疗后与治疗前比较明显更低,差异有统计学意义(t=7.700,P=0.000)。治疗前胆红素水平组间对比差异无统计学意义(t=0.121,P=0.905),治疗后试验组胆红素水平低于对照组,差异无统计学意义(t=0.684,P=0.503)。结论新生儿黄疸治疗中应用蓝光照射时不同的照射方法取得的治疗效果存在一定差异,其中间断蓝光照射的应用效果明显优于持续蓝光照射,其不仅能取得更高的治疗总有效率,还能有效降低患儿治疗过程中的不良反应发生率,具有较高临床价值。Objective To study the therapeutic effect of intermittent and contiuous blue light irradiation on the treatment of neonatal jaundice and the occurrence of adverse reactions during the treatment of children.Methods Convenient selection a total of 50 neonates with jaundice admitted to the hospital were enrolled.The time of treatment was from June 2017 to January 2019.The children were treated with conventional methods after admission,and then the children were treated with blue light.According to the different treatment methods of blue light irradiation,the treatment was divided into 25 cases in the control group and the experimental group.The control group was treated with continuous blue light irradiation,and the children in the experimental group were treated with intermittent blue light irradiation.Both groups continued to be treated.After 3 to 5 d of treatment,it ends.The therapeutic effects of the two groups were evaluated and compared.The incidence of adverse reactions in the two groups was observed and compared,and the bilirubin levels before and after treatment were compared between the two groups.Results The total effective rate of treatment was compared between the two groups.The total effective rate of 96.00%of the treatment group was higher than the total effective rate of 76.00%of the control group.The difference was statistically significant(χ^2=4.153 P=0.042).The incidence of adverse reactions in the test group was 12.00%lower than that in the control group(36.00%),and the difference was statistically significant(χ^2=3.947,P=0.047).The average level of bilirubin before treatment in the experimental group was(271.95±45.28)μmol/L,and the average bilirubin level after treatment was(134.29±24.17)μmol/L,which was significantly lower after treatment than before treatment.The difference was statistically significant(t=8.481,P=0.000).The average level of bilirubin before treatment in the control group was(269.43±48.09)μmol/L,and the average bilirubin level after treatment was(141.27±21.39)μmol/L.T

关 键 词：蓝光 间断照射 持续照射 新生儿黄疸 不良反应 临床疗效 

分 类 号：R5[医药卫生—内科学]