中药汤剂联合药物贴敷对小儿支原体肺炎的临床疗效和免疫功能的影响  

Effects of Chinese medicinal decoction combined with plaster therapy on clinical efficacy and immunological function of children with mycoplasma pneumonia

作　　者：陆玉廷 LU Yuting(Department of Pediatrics,Jiaxing Hospital of TCM,Jiaxing,Zhejiang,314000,China)

机构地区：[1]嘉兴市中医医院儿科,浙江嘉兴314000

出　　处：《中医儿科杂志》2020年第1期57-60,共4页Journal of Pediatrics of Traditional Chinese Medicine

摘　　要：目的观察中药汤剂联合药物贴敷对小儿支原体肺炎的临床疗效和免疫功能的影响。方法选取2017年3月至2018年3月在嘉兴市中医医院儿科就诊的96例支原体肺炎患儿,按照随机数字表法分为治疗组和对照组,各48例。对照组采用抗感染、退热、平喘止咳等常规治疗,治疗组在对照组治疗方法的基础上采用中药汤剂联合药物贴敷治疗,2组均治疗2周后,比较临床症状消失时间和住院时间、细胞免疫功能(T淋巴细胞亚群CD3^+、CD4^+、CD8^+水平及CD4^+/CD8^+值)和不良反应发生情况。结果治疗组咳嗽、发热、肺部湿啰音消失时间和住院时间均明显短于对照组,2组比较,差异有统计学意义(P<0.05)。治疗前,2组的CD3^+、CD4^+、CD8^+和CD4^+/CD8^+值比较,差异均无统计学意义(P>0.05),具有可比性;与同组治疗前比较,治疗后2组CD3^+、CD4^+和CD4^+/CD8^+值均明显升高,CD8^+值下降,且治疗组上述指标改善优于对照组,差异有统计学意义(P<0.05)。治疗组不良反应总发生率为6.24%,对照组为10.41%,2组比较,差异无统计学意义(P>0.05)。结论中药汤剂联合药物贴敷治疗小儿支原体肺炎疗效满意,不仅可以缩短临床症状、体征消失时间和住院时间,而且可以提高患儿免疫功能,且安全性较好。Objective To observe the effects of Chinese medicinal decoction combined with plaster therapy on clinical efficacy and immunological function of children with mycoplasma pneumonia.Methods Ninety-six cases of children with mycoplasma pneumonia consulted in pediatrics department of Jiaxing Hospital of TCM from March 2017 to March 2018 were chosen and divided into treatment group and control group according to random number table method,with 48 cases in each.The control group was given routine treatment including anti-infection,abatement of fever,relieving asthma to stop cough etc.,on this basis,the treatment group was given Chinese medicinal decoction combined with plaster therapy.After the 2 groups were both treated for 2 weeks,the disappearance time of clinical symptoms,length of stay,the cellular immune function(subset of the class of T-cells the levels of CD3^+,CD4^+,CD8^+ and CD4^+/CD8^+ value)and the incidence of adverse reactions were compared.Results The disappearance time of cough,fever,pulmonary wet rale and length of stay in the treatment group were all significantly shorter than those in the control group,and the difference between the two groups was statistically significant(P<0.05).Before treatment,the difference was not statistically significant in CD3^+,CD4^+,CD8^+ and CD4^+/CD8^+ value between the two groups(P>0.05),and they were comparable.Compared with the same group before treatment,CD3^+,CD4^+ and CD4^+/CD8^+ value significantly increased,while CD8^+ value decreased after treatment in the two groups,moreover,the improvement of the above-mentioned index in the treatment group was superior to that in the control group,and the difference was statistically significant(P<0.05).The total incidence rate of adverse reactions in the treatment group was 6.24%,that of the control group was 10.41%,and the difference between the two groups was not statistically significant(P>0.05).Conclusion Chinese medicinal decoction combined with plaster therapy in the treatment of children with mycoplasma pneumonia has

关 键 词：支原体肺炎 小儿 中药汤剂 药物贴敷 免疫功能 临床观察 

分 类 号：R256.1[医药卫生—中医内科学]