腹腔镜卵巢囊肿剔除术对女性卵巢储备功能的 影响分析  

Analysis of the Effect of Laparoscopic Ovarian Cystectomy on Female Ovarian Reserve Function

作　　者：赵伟雪 吕忠梅 ZHAO Wei-xue;LYU Zhong-mei(Department of Gynecology,Tacheng People's Hospital,Tacheng,Xinjiang,834700 China)

机构地区：[1]新疆塔城地区塔城市人民医院妇科,新疆塔城834700

出　　处：《系统医学》2020年第1期134-136,共3页Systems Medicine

摘　　要：目的探讨腹腔镜下卵巢囊肿剔除术治疗子宫内膜异位囊肿对女性卵巢储备功能的影响。方法选取2013年4月—2018年7月在该院妇产科诊治的72例子宫内膜异位囊肿患者为研究对象,根据临床资料中患者手术方式分为观察组和对照组,对照组采用腹腔镜下囊肿切开放液术治疗,观察组采用腹腔镜卵巢囊肿剔除术,术后两组患者均给予促性腺激素激动剂(GnRH-a)治疗。观察并记录两组术前、术后6半年卵巢功能指标:血清卵泡刺激素(FSH)、黄体生成素(LH)、雌二醇(E2)的水平、基础卵泡数量、卵巢体积变化,比较两组复发率和月经、术后1年成功再妊娠情况。结果观察组LH(4.15±0.44)mIU/mL低于对照组(4.83±0.57)mIU/mL,观察组E2(48.22±4.22)pmol/L低于对照组(54.65±4.38)pmol/L(P<0.05),术后半年两组FSH指标差异无统计学意义(P>0.05);观察组基础卵泡数量(6.1±2.2)个低于术前(8.2±3.2)个;观察组卵巢平均体积(5.69±0.88)cm3低于术前(12.20±1.26)cm^3(P<0.05)。观察组术后1年妊娠率77.8%显著高于对照组36.1%,而复发率5.6%明显低于对照组22.2%,差异有统计学意义(χ^2=12.746、4.181,P<0.05)。结论行腹腔镜卵巢囊肿剔除术患者术后短期内卵巢储备功能受到一定影响,与传统开腹手术相比,腹腔镜卵巢囊肿剔除术在患者妊娠率、术后恢复及复发率方面仍然具有明显优势。Objective To investigate the effect of laparoscopic ovarian cystectomy on endometriotic cysts in female ovarian reserve.Methods 72 patients with endometriotic cysts who were treated in the department of obstetrics and gynecology from April 2013 to July 2018 were selected as subjects.The control group was treated with laparoscopic cystectomy,while the observation group was treated with laparoscopic ovarian cystectomy.Both groups were treated with gonadotropin agonist(GnRH-a).Observe and record the ovarian function indexes of the two groups before and after 6 months:serum follicle stimulating hormone(FSH),luteinizing hormone(LH),estradiol(E2)levels,basal follicles,ovarian volume changes.Compare two groups'recurrence rate and successful re-pregnancy in menstruation and 1 year after surgery.Results The LH of the observation group was(4.15±0.44)mIU/mL,lower than that of the control group(4.83±0.57)mIU/mL,and the observation group E2(48.22±4.22)pmol/L was lower than the control group(54.65±4.38)pmol/L(P<0.05),there was no statistically significant difference in FSH index between the two groups(P>0.05).The number of basal follicles in the observation group(6.1±2.2)was lower than that before surgery(8.2±3.2);the average volume of ovary in the observation group(5.69±0.88)cm3 was lower than preoperative(12.20±1.26)cm^3(P<0.05).The 1-year pregnancy rate of the observation group(77.8%)was significantly higher than that of the control group by 36.1%,and the recurrence rate of 5.6%was significantly lower than that of the control group(22.2%)and the difference was statistically significant(χ^2=12.746,4.181,P<0.05).Conclusion The ovarian reserve function of patients undergoing laparoscopic ovarian cystectomy is affected in a short time.Compared with traditional open surgery,laparoscopic ovarian cyst removal still has obvious advantage of the pregnancy rate,postoperative recovery and recurrence rate.

关 键 词：腹腔镜 卵巢囊肿 剔除术 卵巢储备功能 影响 

分 类 号：R59[医药卫生—内科学]