安徽省某胃癌高发县40~69岁居民食盐及腌渍食物摄入与幽门螺杆菌感染状况的调查与分析  

Relationship between the intake of salt and salted food and the infection of Helicobacter pylori in 40-69 years old local residents in a county with high gastric cancer risk in Anhui Province

作　　者：吴寒寒 王陈 汪光军 赵奇红[1] 李李[1] 陈文军[1] 博庆丽[1] 胡传来[1] 胡安拉[1] WU Han-han;WANG Chen;WANG Guang-jun;ZHAO Qi-hong;LI Li;CHEN Wen-jun;BO Qing-li;HU Chuan-lai;HU An-la(Department of Nutrition and Food Hygiene,School of Public Health,Anhui Medical University,Hefei 230032,China)

机构地区：[1]安徽医科大学公共卫生学院营养与食品卫生学系,合肥230032

出　　处：《中华疾病控制杂志》2020年第2期164-169,共6页Chinese Journal of Disease Control & Prevention

基　　金：国家自然科学基金(81502806)。

摘　　要：目的了解安徽省某胃癌高发县40~69岁常住居民食盐及腌渍食物摄入与幽门螺杆菌(helicobacter pylori,Hp)感染之间的关系。方法 2015年7月-2018年8月在安徽省庐江县40~69岁居民中进行问卷调查和Hp血清学检测,问卷着重调查食盐摄入量及腌渍食物食用频率,按性别分析Hp感染与危险因素之间的关系,单因素及多因素Logistic回归模型分析探讨相关影响因素。结果调查对象整体Hp感染率为50.07%,男性居民年龄、体质指数(body mass index,BMI)、婚姻状况、文化程度、工作、劳动强度、经济收入与Hp感染均无关(均有P>0.05),女性居民BMI与Hp感染相关(χ~2=13.454,P=0.001)。男性居民中,饮酒是Hp感染的危险因素(OR=1.789,95%CI:1.188~2.694,P=0.003),但调整饮酒变量后的多因素分析显示男性食盐摄入量高及腌渍食物摄入频率高对Hp感染均无影响(均有P>0.05);女性调查对象调整BMI变量后,食盐摄入量高(≥9 g/d)是女性感染Hp的危险因素(OR=1.462,95%CI:1.060~2.015,P=0.021),腌渍食物摄入频率高(≥1次/d)是女性感染Hp的危险因素(OR=1.560,95%CI:1.021~2.383,P=0.040)。结论在安徽省某胃癌高发县,食盐摄入量高(≥9 g/d)及腌渍食物摄入频率高(≥1次/d)是40~69岁当地女性居民感染Hp的危险因素。Objective The aim of the present study was to investigate the relationship between the intake of salt and salted food and the infection of Helicobacter pylori(Hp)among 40-69 years old local residents in a county with high gastric cancer risk in Anhui province.Methods From July 2015 to August 2018,we conducted a questionnaire and a serological test for Hp among 40-69 years old local residents in Lujiang county,Anhui province.The questionnaire focused on the consumptions of salt and salted food.The relationship between Hp infection and risk factors was analyzed by gender.Univariate and multivariate logistic regression analysis were used to analyze the relevant influencing factors.Results The Hp infection rate of total local residents was 50.07%.Among male subjects,age,body mass index(BMI),marital status,educational level,job,labor intensity and income had no link to Hp infection(all P>0.05).But among female subjects,BMI was associated with Hp infection(χ~2=13.454,P=0.001).Besides,alcohol consumption was a risk factor for Hp infection in male subjects(OR=1.789,95%CI:1.188-2.694,P=0.003).But,high intake of salt and salted food had no effect on Hp infection after adjustment for alcohol consumption variable in men using multivariate analysis(all P>0.05).After adjusted for BMI variable among female individuals,high salt intake(≥9 g/day)(OR=1.462,95%CI:1.060-2.015,P=0.021)and the high salted food intake(≥1 times/day)were risk factors for Hp infection in women(OR=1.560,95%CI:1.021-2.383,P=0.040).Conclusions In one county with high gastric cancer risk in Anhui province,high salt intake(≥9 g/day)and high salted food intake(≥1 times/day)are risk factors for Hp infection among 40-69 years old female local residents.

关 键 词：幽门螺杆菌感染 高盐饮食 腌渍食物 胃癌 

分 类 号：R181[医药卫生—流行病学]