局麻下支气管镜钬激光治疗大气道狭窄的临床评价  

Application and safety evaluation of holmium laser in the central airway obstruction

作　　者：王成 刘庆华 赵娜 林殿杰[4] Cheng Wang;Qing-hua Liu;Na Zhao;Dian-jie Lin(Department of Respiratory Medicine,Xuzhou Cancer Hospital,Xuzhou,Jiangsu 221005,China;Department of Respiratory Medicine,Shanghai East Hospital,Tongji University,Shanghai 200120,China;Department of Respiratory Medicine,the Third Provincial Hospital of Shandong,Ji’nan,Shandong 250031,China;Department of Respiratory and Critical Care Medicine,Shandong Provincial Hospital affiliated to Shandong University,Ji’nan,Shandong 250014,China)

机构地区：[1]徐州市肿瘤医院呼吸内科,江苏徐州221005 [2]同济大学附属东方医院(上海市东方医院)呼吸内科,上海200120 [3]山东省立第三院呼吸内科,山东济南250031 [4]山东大学附属省立医院呼吸与危重症医学科,山东济南250014

出　　处：《中国内镜杂志》2020年第3期77-81,共5页China Journal of Endoscopy

摘　　要：目的观察局麻支气管镜下钬激光治疗大气道狭窄的近期疗效及安全性。方法收集山东大学附属省立医院2014年1月-2016年5月46例钬激光治疗的大气道狭窄患者共85例次,均经CT或气管镜检查证实,后予以钬激光治疗或联合冷冻或球囊扩张等处理,术中予以低流量吸氧并严密监测生命体征,术后定期复查并随访。结果完全缓解5例次(5.9%),显著缓解69例次(81.2%),部分缓解11例次(12.9%),治疗失败0例次(0.0%),总体有效率100.0%;无死亡、大出血、气道内着火等严重并发症。结论钬激光联合冷冻、球囊扩张治疗大气道狭窄安全性高,并发症少,近期疗效可靠。Objective To evaluate the efficacy and safety of holmium laser in the therapy of central airway stenosis.Methods We collected 46 patients with central airway obstruction who was given 85 holmium laser treatments.All the airway stenosis were confirmed by CT or bronchoscopy.All the patients were treated with holmium laser treatment or combined with freezing or balloon dilation,and given low-flow oxygen and monitored for vital signs during the operation.Regular reexamination and follow-up were conducted after the operation.Results Total efficiency ratio is as high as 100.0%.Five cases (5.9%) completely relieved,69 (81.2%) significantly relieved,11 (12.9%) have partial response.No serious complications were reported.Conclusion Holmium laser is a safety method with satisfactory result in management of benign central airway stenosis.

关 键 词：大气道狭窄 钬激光 近期疗效 安全性 并发症 

分 类 号：R562[医药卫生—呼吸系统]