窄谱强脉冲激光联合克痤隐酮凝胶治疗炎症性痤疮的临床效果  

Clinical effect of narrow-spectrum intense pulsed laser combined with Kecuoyintong Gel in the treatment of inflammatory acne

作　　者：蔡杏仪 张方布 CAI Xing-yi;ZHANG Fang-bu(Department of Dermatology,Foshan Sanshui Disease Control Institute,Guangdong Province,Foshan 528100,China)

机构地区：[1]广东省佛山市三水区疾病防治所皮肤科,广东佛山528100

出　　处：《中国当代医药》2020年第6期57-59,共3页China Modern Medicine

摘　　要：目的探讨窄谱强脉冲激光联合克痤隐酮凝胶治疗炎症性痤疮的临床效果。方法选取2017年2月~2019年2月在我院治疗的174例炎症性痤疮患者作为研究对象,按随机数字表法分为观察组和对照组,每组各87例。观察组用窄谱强脉冲激光和克痤隐酮凝胶联合治疗,对照组仅用克痤隐酮凝胶治疗,比较两组的临床效果、不良反应发生情况、皮损评分。结果观察组临床总有效率(98.85%)高于对照组(91.95%),差异有统计学意义(P<0.05);两组均未发生严重不良反应;治疗前,两组皮损评分[(27.28±4.97)分vs.(27.27±4.96)分],差异无统计学意义(P>0.05);治疗后,观察组皮损评分[(8.85±2.44)分]低于对照组[(11.32±2.76)分],差异有统计学意义(P<0.05);两组治疗后皮损评分低于治疗前,差异有统计学意义(P<0.05)。结论使用窄谱强脉冲激光和克痤隐酮凝胶联合治疗炎症性痤疮的效果更明显,不良反应的抑制更好,适用在临床大面积推广。Objective To investigate the clinical effect of narrow-spectrum intense pulsed laser combined with Kecuoyintong Gel in the treatment of inflammatory acne.Methods A total of 174 patients with inflammatory acne treated in our hospital from February 2017 to February 2019 were selected and divided into control group and observation group by random number table method,87 cases in each group.In the observation group,patients were treated with narrow-spectrum intense pulsed laser combining with Kecuoyintong Gel.In the control group,patients were treated with Kecuoyintong Gel alone.The clinical effects,adverse reactions,and skin lesion scores were compared between the two groups.Results The total clinical effective rate of the observation group was 98.85%,higher than that of the control group accounting for 91.95%,and the difference was statistically significant(P<0.05).No serious adverse reactions occurred in the two groups.There was no significant difference in the skin lesion scores of the two groups([27.28±4.97]points vs.[27.27±4.96]points)before treatment(P>0.05).After treatment,the skin lesion score of the observation group was(8.85±2.44)points,lower than that of the control group for(11.32±2.76)points,with statistical difference(P<0.05).The lesion scores of the two groups after treatment were lower than those before treatment,with statistical differences(P<0.05).Conclusion The combination of narrow-spectrum intense pulsed laser and Kecuoyintong Gel shows more obvious effects and can better inhibit adverse reactions,which is applicable to large-scale clinical promotion.

关 键 词：炎症性痤疮 克痤隐酮凝胶 窄谱强脉冲激光 临床研究 

分 类 号：R758.733[医药卫生—皮肤病学与性病学]