芬太尼和小剂量地佐辛分别联合丙泊酚在无痛人工流产术中的麻醉效果比较  

Anesthetic effect comparison between Fentanyl and low-dose Dextrozine combined with Propofol in painless artificial abortion

作　　者：李书涛 朱青丹 LI Shu-tao;ZHU Qing-dan(Department of Anesthesiology,Bao′an District Maternal and Child Health Hospital of Shenzhen City,Ji′nan University,Guangdong Province,Shenzhen 518102,China;Department of Obstetrics,Bao′an District Maternal and Child Health Hospital of Shenzhen City,Ji′nan University,Guangdong Province,Shenzhen 518102,China)

机构地区：[1]暨南大学附属深圳市宝安区妇幼保健院麻醉科,广东深圳518102 [2]暨南大学附属深圳市宝安区妇幼保健院产科,广东深圳518102

出　　处：《中国当代医药》2020年第6期134-136,共3页China Modern Medicine

摘　　要：目的研究芬太尼和小剂量地佐辛分别联合丙泊酚在无痛人工流产术中的麻醉效果。方法选取2018年6月~2019年6月我院妇科门诊收治的需行人工流产术的200例患者作为研究对象,根据随机数字表法将其分为实验组和对照组,每组各100例。对照组患者给予芬太尼联合丙泊酚进行麻醉,实验组患者给予小剂量地佐辛联合丙泊酚进行麻醉。比较两组患者术前、麻醉后和清醒后的心率、平均动脉压和血氧饱和度,并观察两组患者的镇痛效果及术后不良反应发生情况。结果实验组患者术前、麻醉后和清醒后的心率、平均动脉压、血氧饱和度与对照组比较,差异无统计学意义(P>0.05)。实验组患者的镇痛总有效率为98.00%,高于对照组的90.00%,差异有统计学意义(P<0.05)。实验组患者的不良反应总发生率低于对照组,差异有统计学意义(P<0.05)。结论小剂量地佐辛联合丙泊酚在无痛人工流产术中的临床麻醉效果好,患者生命体征平稳,能有效提高镇痛效果,降低疼痛评分,且术后不良反应少。Objective To study the anesthetic effect between Fentanyl and low-dose Dextrozine combined with Propofol in painless artificial abortion.Methods A total of 200 patients undergoing artificial abortion in gynecological outpatient clinic of our hospital from June 2018 to June 2019 were selected as research objects,and they were divided into experimental group and control group according to the random number table method,with 100 cases in each group.Patients in the control group were given Fentanyl combined with Propofol for anesthesia,and patients in the experimental group were given low-dose Dextrozine combined with Propofol for anesthesia.The heart rate,mean arterial pressure,and blood oxygen saturation before surgery,after anesthesia,and after waking in two groups of patients were compared.The analgesic effect and incidence of postoperative adverse reactions in two groups of patients were observed.Results There were no significant differences in heart rate,mean arterial pressure,and blood oxygen saturation between the experimental group and the control group before surgery,after anesthesia,and after waking(P>0.05).The total effective rate of analgesia in the experimental group was 98.00%,which was higher than the 90.00%in the control group,and the difference was statistically significant(P<0.05).The total incidence rate of adverse reactions in the experimental group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion Low-dose Dextrozine combined with Propofol for anesthesia has a good clinical effect in painless artificial abortion.The patients′vital signs are stable,which can effectively improve the analgesic effect,reduce the pain score,and have fewer adverse reactions after surgery.

关 键 词：芬太尼 小剂量地佐辛 丙泊酚 无痛人工流产术 麻醉 

分 类 号：R614[医药卫生—麻醉学]