综合性睡眠干预对小细胞肺癌化疗患者癌因性疲乏与睡眠质量的作用  

Effect of comprehensive sleep intervention on cancer-related fatigue and sleep quality in the patients with small cell lung cancer undergoing chemotherapy

作　　者：冯莉梨 杨希[1] 徐慧芳[2] FENG Lili;YANG Xi;XU Huifang(Health Management Center,Taizhou Central Hospital of Zhejiang,Taizhou318000,China;Department of Thoracic Surgery,Taizhou Central Hospital of Zhejiang,Taizhou318000,China)

机构地区：[1]浙江省台州市中心医院健康管理中心,浙江台州318000 [2]浙江省台州市中心医院胸外科,浙江台州318000

出　　处：《中国现代医生》2020年第4期87-90,共4页China Modern Doctor

基　　金：浙江省中医药科技计划项目(2018ZB135)。

摘　　要：目的探讨综合性睡眠干预对小细胞肺癌(SCLC)化疗患者癌因性疲乏与睡眠质量的作用。方法选取2016年7月~2018年10月化疗的SCLC患者共90例,随机分为干预组和对照组各45例。两组患者均予以包括知识宣教、认知干预、心理干预、饮食指导和用药干预等常规干预措施,干预组患者再加综合性的睡眠干预措施。两组患者干预时间均8周,观察并比较两组患者干预前与干预8周后癌因性疲乏指标[Piper疲乏修订量表]与睡眠质量指标[匹兹堡睡眠质量指数量表(PSQI)]评分的变化。结果干预8周后,两组患者行为疲乏、情感疲乏、躯体疲乏和认知疲乏等Piper疲乏评分较前显著降低(P<0.05或P<0.01),且干预组下降幅度与对照组比较更显著(P<0.05);同时两组患者PSQI评分均较前显著降低(P<0.05或P<0.01),且干预组患者下降幅度与对照组比较更显著(P<0.05)。结论综合性睡眠干预用于SCLC患者不仅可缓解患者的癌因性疲乏症状,而且可明显改善睡眠质量,纠正其睡眠障碍。Objective To investigate the effects of comprehensive sleep intervention on cancer-related fatigue and sleep quality in the patients with small cell lung cancer(SCLC)undergoing chemotherapy.Methods A total of 90 SCLC patients who underwent chemotherapy from July 2016 to October 2018 were selected,and randomly divided into intervention group and control group,with 45 patients in each group.Both groups of patients were given routine interventions such as knowledge education,cognitive intervention,psychological intervention,dietary guidance,and medication intervention.Patients in the intervention group were further given a comprehensive sleep intervention.The intervention lasted for 8 weeks for both groups.The changes of cancer-fatigue index[Piper Fatigue Revision Scale]and sleep quality indicators[Pittsburgh Sleep Quality Index Number Table(PSQI)]scores were observed and compared before intervention and 8 weeks after intervention in both groups.Results After 8 weeks of intervention,the Piper fatigue scores,including behavioral fatigue,emotional fatigue,physical fatigue and cognitive fatigue,were significantly lower than those before intervention in both groups(P<0.05 or P<0.01),and the decreases in the intervention group were more significant than those in the control group(P<0.05);at the same time,the PSQI scores in both groups were significantly lower than those before the intervention(P<0.05 or P<0.01),and the decreases in the intervention group were more significant than those in the control group(P<0.05).Conclusion Comprehensive sleep intervention for the patients with SCLC can not only alleviate the symptoms of cancer-related fatigue,but also significantly improve sleep quality and correct sleep disorders.

关 键 词：小细胞肺癌 化疗 综合性睡眠干预 癌因性疲乏 睡眠质量 

分 类 号：R473.73[医药卫生—护理学]