巴戟天属植物环烯醚萜类化学成分及生物活性研究进展  

Research on chemical components and biological activities of the iridoids in Morinda genus

作　　者：沈燚 张奇 刘梦琴 何玉琼 辛海量 秦路平 张巧艳 SHEN Yi;ZHANG Qi;LIU Mengqin;HE Yuqiong;XIN Hailiang;QIN Luping;ZHANG Qiaoyan(Department of Pharmacognosy,School of Pharmacy,Naval Medical University,Shanghai 200433,China;School of Pharmacy,Fujian University of Traditional Chinese Medicine,Fuzhou 350122,China;School of Pharmacy,Zhejiang University of Traditional Chinese Medicine,Hangzhou 310053,China)

机构地区：[1]海军军医大学药学院生药学教研室,上海200433 [2]福建中医药大学药学院,福州350122 [3]浙江中医药大学药学院,杭州310053

出　　处：《药学实践杂志》2020年第2期110-114,119,共6页Journal of Pharmaceutical Practice

基　　金：国家自然科学基金项目(U1505226)。

摘　　要：茜草科巴戟天属植物在国内外医药中有广泛的应用,主要的药用部位包括根、茎、叶、枝和种子等。通过在线数据库的搜索,本文对巴戟天属环烯醚萜类化学成分及生物活性进行研究总结。迄今为止,已鉴定巴戟天属环烯醚萜类化合物50余种,多具有抗炎镇痛、抗氧化、抗肿瘤、骨保护作用等多种生物活性,以期为巴戟天属环烯醚萜类成分的进一步开发利用提供理论依据。Morinda genus of Rubiaceae has been widely used in medicine at home and abroad. Many parts of Morinda tree are utilized in research, mainly including roots, stems, leaves, branches and seeds. Through the research of online databases, the chemical components and biological activities of the iridoids in Morinda genus were summarized in this paper. Up to now, more than 50 kinds of iridoids have been identified. In addition, more and more studies proved that Morinda iridoids might benefit human via such anti-inflammatory, antinociceptive, anti-oxidation, anti-tumor and bone protection. The theoretical basis was provided for the further development and utilization of the iridoids in Morinda genus.

关 键 词：茜草科 巴戟天属 环烯醚萜 化学成分 生物活性 

分 类 号：R284[医药卫生—中药学]