糖尿病性硬肿病一例报告并文献复习  

A case report of scleredema diabeticorum and literature review

作　　者：申奥 景娜 赵琳琳[1] 丁晓煦 韦俊芳[1] 赵艳艳[1] SHEN Ao;JING Na;ZHAO Linlin(Department of Endocrinology and Metabolism,The First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China)

机构地区：[1]郑州大学第一附属医院内分泌与代谢病科,450052

出　　处：《中国糖尿病杂志》2020年第2期143-146,共4页Chinese Journal of Diabetes

摘　　要：糖尿病性硬肿病(SD)是一种累及结缔组织的慢性糖尿病并发症,多发于血糖控制较差的肥胖糖尿病患者。临床表现主要为背、颈、肩部皮肤逐渐粗糙、硬化,皮肤组织活检可明确诊断,部分患者因早期未出现典型症状易被误诊、漏诊。本文报道1例SD患者的临床诊治经过,回顾分析临床表现、组织学特点、相关治疗手段及可能的发病机制,旨在加强临床医生对该病的认识,以早期识别和预防严重并发症。Scleredema diabeticorum(SD)is a chronic connective tissue disease associated with diabetes mellitus,especially in obese diabetic patients with poorly glycemic control.SD usually occurs in the back,neck,and shoulders,with the skin becoming rough and even hardened.Skin tissue biopsy can help to confirm the diagnosis.Some patients were misdiagnosed and missed due to the absence of typical symptoms in early course of the disease.This article reported the diagnosis and treatment of a SD patient and reviewed its possible pathogenesis,clinical manifestations,histological features and related treatments to deepen the clinician's understanding of the disease.

关 键 词：糖尿病性硬肿病 临床特点 治疗方法 历史文献 

分 类 号：R587.2[医药卫生—内分泌]