全膝关节置换术金属植入物并发症的研究进展  

Research progress of complications of metal implants in total knee arthroplasty

作　　者：韩广弢 高冯(综述) 李皓桓(审校)[1] Han Guangtao;Gao Feng;Li Haohuan(Department of Orthopedics, People's Hospital of Wuhan university, Hubei Province, Wuhan 430060,China)

机构地区：[1]武汉大学人民医院骨科,430060

出　　处：《疑难病杂志》2020年第4期413-416,共4页Chinese Journal of Difficult and Complicated Cases

基　　金：国家自然科学基金资助项目(81171760);湖北省自然科学基金资助项目(2017CFB700)。

摘　　要：临床上常错误地将术语“超敏”和“过敏”同义使用,尽管存在某种关系,但未发现因过敏而导致全膝关节置换术植入物失败的任何证据。但是,越来越多的证据表明,松动与金属离子产生存在联系。这不是过敏反应,而是潜在的问题。在缺乏证据的情况下,对于全膝关节置换术中使用金属后存在皮肤敏感性的患者,没有理由使用“低变应原性”植入物。现就有关过敏和超敏反应是否与全膝关节置换术植入物选择有关的相关文献进行综述。The term"hypersensitivity"and"hypersensitivity"are often used synonymously in clinical practice.Although there is a certain relationship,no evidence of the failure of total knee arthroplasty implants due to hypersensitivity has been found.However,more and more evidences show that loosening is related to the production of metal ions.It's not an allergic reaction,it's a potential problem.In the absence of evidence,there is no reason to use"hypoallergenic"implants in patients with skin sensitivity following the use of metal in total knee arthroplasty.This article reviews the literature on whether hypersensitivity and hypersensitivity are related to implant selection in total knee arthroplasty.

关 键 词：全膝关节置换术 植入物 过敏反应 金属离子 

分 类 号：R687.4[医药卫生—骨科学]