香豆素类双酰腙荧光探针的合成及对Cu^2+的识别性能  

Synthesis and Evaluation of Dicoumarin Acylhydrazone Derivatives as Fluorescent Probes for Cu^2+

作　　者：王海娜 张慧 俞天智 赵玉玲[2] Wang Haina;Zhang Hui;Yu Tianzhi;Zhao Yuling(Key Laboratory of Opto-Electronic Technology and Intelligent Control(Ministry of Education),Lanzhou Jiaotong University,Lanzhou,730070;School of Chemical and Biological Engineering,Lanzhou Jiaotong University,Lanzhou,730070)

机构地区：[1]兰州交通大学光电技术与智能控制教育部重点实验室,兰州730070 [2]兰州交通大学化学与生物工程学院,兰州730070

出　　处：《化学通报》2020年第3期240-245,252,193,共8页Chemistry

基　　金：国家自然科学基金项目(51563014);甘肃省自然基金项目(1606RJZA018)资助。

摘　　要：设计合成了2种以香豆素为荧光团、酰腙为识别基团的双香豆素双酰腙类荧光探针,并对其进行了结构表征及光谱性能研究。结果表明,探针对Cu^2+具有高选择性和高灵敏度,表现出明显的荧光猝灭效应,探针与Cu^2+以1∶2的结合比相互作用,对Cu^2+检测限为10^-9mol/L。Two fluorescent probes,(N1′,E,N3′,E)-N1′,N3′-bis((7-N,N-diethylaminocoumarin-3-yl)methylene)malonohydrazide and(N1′E,N4′E)-N1′,N4′-bis((7-N,N-diethylaminocoumarin-3-yl)methylene)succinohydrazide,bearing acylhydrazone group as binding site and coumarin group as the fluorescence signal group were synthesized and characterized by conventional techniques.These probes showed notable fluorescence turn-off response for Cu^2+over other metals ions.The probes and Cu^2+formed 1∶2 coordination complexes according to spectroscopy data and Job’s plots.Further study demonstrated that the detection limit of Cu^2+for the probes was as low as 10^-9mol/L.

关 键 词：CU^2+ 双香豆素 酰腙 荧光探针 

分 类 号：X832[环境科学与工程—环境工程]