纳米钯催化芳基卤化物与四苯基硼酸钠的水相高效偶联反应研究  

Palladium Nanoparticals Catalyzed Atom-Efficient Coupling Reaction of Aryl Halides with Sodium Tetraphenylborate

作　　者：胡贝 张源民 王天昀 杜正银[1] HU Bei;ZHANG Yuan-min;WANG Tian-yun;DU Zheng-yin(School of Chemistry and Chemical Engineering,Northwest Normal University,Lanzhou 730070,China)

机构地区：[1]西北师范大学化学化工学院,甘肃兰州730070

出　　处：《聊城大学学报（自然科学版）》2020年第3期67-71,共5页Journal of Liaocheng University:Natural Science Edition

基　　金：国家自然科学基金项目(21762039)资助。

摘　　要：使用原位生成的钯纳米颗粒作催化剂,芳基溴化物/碘化物和四苯基硼酸钠在聚乙二醇/水混合溶剂中发生快速、高效的Suzuki-Miyaura交叉偶联反应.该反应具有较高的原子利用率,四苯基硼酸钠的四个苯基均参与反应,并以非常高的收率得到了多官能化联芳化合物,催化剂体系可循环使用多次.该方法绿色环保,反应效率高.A rapid and highly efficient ligand-free Suzuki-Miyaura cross-coupling reaction occurs between aryl halides and sodium tetraphenylborate using in situ generated palladium nanoparticles as a catalyst from palladium chloride and PEG400.The reaction showshigh atom utility,as four phenyl groups of sodium tetraphenylboratecan participate in the reaction,and a series of functionalized biarylswere prepared in excellent yield in PEG400/H 2O.

关 键 词：氯化钯 四苯硼酸钠 Suzuki-Miyaura反应 水相反应 芳基卤化物 

分 类 号：O614[理学—无机化学]