重型颅脑损伤患者行鼻胃管与鼻肠管肠内营养所致并发症Meta分析  

Complications associated with enteral nutrition by nasogastric and nasointestinal tube in severely brain-injured patients:a meta-analysis

作　　者：王兰 李清念 黄素芳[2] 熊杰[2] 刘俊雅[2] Wang Lan;Li Qingnian;Huang Sufang;Xiong Jie;Liu Junya(Nursing Department,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China)

机构地区：[1]华中科技大学同济医学院附属同济医院护理部,湖北武汉430030 [2]华中科技大学同济医学院附属同济医院重症医学科,湖北武汉430030

出　　处：《护理学杂志》2020年第3期80-83,共4页Journal of Nursing Science

摘　　要：目的系统评价重型颅脑损伤患者行鼻胃管与鼻肠管肠内营养所致并发症情况。方法计算机检索PubMed、OVID、Cochrane Library、中国期刊全文数据库(CNKI)以及万方数据库中鼻胃管与鼻肠管肠内营养所致并发症相关的随机对照试验(RCT),筛选纳入15篇RCT文献并进行质量评估,采用Revman5.3软件行Meta分析。结果15篇RCT文献共1059例样本。Meta分析结果显示,鼻肠管肠内营养所致反流、误吸、肺部感染及腹胀发生率显著低于鼻胃管肠内营养(均P<0.01),腹泻和消化道出血发生率差异无统计学意义(均P>0.05)。结论采用鼻肠管行肠内营养支持,患者反流、误吸、肺部感染及腹胀发生率低于鼻胃管肠内营养。Objective To systematically evaluate the complications associated with enteral nutrition by nasogastric and nasointestinal tube in severely brain-injured patients.Methods Randomized controlled trials regarding the complications of enteral nutrition by nasogastric and nasointestinal tube in severely brain-injured patients were retrieved in such electronic databases as PubMed,OVID,Cochrane Library,Chinese Journal Full-text Database(CNKI)and Wanfang database.Quality of the literature was measured and Revman5.3 software was employed to conduct meta-analysis.Results Fifteen RCT studies were included involving 1059 samples.The results of meta-analysis showed that the incidence rates of reflux,aspiration,pulmonary infection and bloating were significantly lower in patients using nasointestinal tube compared with those using nasogastric tube(P<0.01 for all),but there were no significant differences in diarrhea and gastrointestinal bleeding(P>0.05 for both).Conclusion Nasointestinal tube is superior to nasogastric tube in enteral nutrition,which can effectively reduce the incidence of reflux,aspiration,pulmonary infection and bloating in patients with severe head injury.

关 键 词：重型颅脑损伤 肠内营养 鼻肠管 鼻胃管 并发症 META分析 

分 类 号：R473.6[医药卫生—护理学] R472.9[医药卫生—临床医学]